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OBJECTIVES To evaluate the effect of late diagnosis and other factors on outcome of paediatric bacterial meningitis (BM) and recommend appropriate intervention. DESIGN Case series. SETTING University of Calabar Teaching Hospital, Calabar, Nigeria. SUBJECTS 62 consecutive BM patients aged two months to 16 years admitted between 1991 and 1994. MAIN(More)
BACKGROUND Rabies is a preventable zoonosis with the highest case fatality of any disease in the world. In the developing world, it is transmitted mainly by dog bites. In parts of southern Nigeria, dog meat is a delicacy. OBJECTIVE To highlight trade in stray dogs as a major risk factor for rabies in animals and humans in south-south Nigeria. METHOD(More)
Gliomas are the commonest primary brain tumours in adults. They are usually classified and graded according to the criteria by the World Health Organisation. High-grade gliomas are the most malignant primary brain tumours. Conventional therapies include surgery, radiotherapy, and chemotherapy. The tumours often demonstrate high levels of resistance to these(More)
A prospective observational study was carried out to describe the pattern of pulmonary complications in hospitalized patients with Human Immune-deficiency Virus (HIV) infection at the University of Calabar Teaching Hospital, Calabar between January 2005 to December 2006. One hundred and twenty-four patients which consists 60 males and 64 females, aged(More)
Profile of Neurologic Emergencies At The Accident & Emergency Department of A Tertiary Hospital in South Nigeria Ekanem Eyo PHILIP-EPHRAIM, Komomo I EYONG, Sidney K OPARAH, Uduak E WILLIAMS, Ndifreke UDONWA, Abraham N GYUSE, Rhoda Philip EPHRAIM Department of Internal Medicine, University of Calabar Teaching Hospital, Calabar, Nigeria Department of Family(More)
Multiple sclerosis is an autoimmune disease of the central nervous system characterized by inflammatory demyelination and axonal degeneration. It is the commonest cause of permanent disability in young adults. Environmental and genetic factors have been suggested in its etiology. Currently available disease modifying drugs are only effective in controlling(More)
OBJECTIVES Older people are at increasing risk of HIV/AIDS and other sexually transmitted diseases. The use of condoms which can protect both partners from sexually transmitted infections (STIs) including HIV during vaginal and anal sex is mostly neglected by them. In fact, postmenopausal women may not see the need for condom use when they are no longer at(More)
BACKGROUND Neurologic disorders represent a major burden of disease globally and the spectrum ranges from noncommunicable disorders like stroke and neurodegenerative disorders to central nervous system infections. OBJECTIVE The purpose of the study is to assess the burden of neurological diseases in a tropical environment. METHODS A one year(More)
Motor neuron disease is a neurodegenerative disease characterized by loss of upper motor neuron in the motor cortex and lower motor neurons in the brain stem and spinal cord. Death occurs 2-4 years after the onset of the disease. A complex interplay of cellular processes such as mitochondrial dysfunction, oxidative stress, excitotoxicity, and impaired(More)