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The aim of the present study was to investigate the roles of tyrosine kinase (TK) in the insulin action on cell volume in fetal rat (20-day gestational age) type II pneumocyte. Insulin (100 nmol/l) increased cell volume, and this insulin (100 nmol/l) action was completely blocked by 50 μmol/l bumetanide (BMT) and 10 μmol/l amiloride (AML). This observation(More)
The effects of hyperthermia on blood volume and effective vascular compliance were studied in control and heat acclimated rats (three weeks at 32°C and 50% R.H.). Experiments were performed on conscious rats whose abdominal aorta and both jugular veins were cannulated. Continuous changes in blood volume (BV) were monitored by measuring51Cr tagged(More)
Two patients with acute promyelocytic leukemia (APL) were found to have chromosomal translocations in their leukemic cells; one had a 46,XX,t(7;17)(q36;q22) and another a 46,XY,t(1;17)(p36;q21) karyotype. These two cases of APL seem to be the first involving variant translocations instead of the standard t(15q+; 17q-) translocation. The present cases(More)
The effects of rat atrial natriuretic peptide (rANP) on blood volume (BV) were determined by the continuous measurement of BV, mean arterial pressure (MAP), and central venous pressure (CVP). Immediately after a single-bolus injection of rANP-(1-28), 1 nmol/100 g body wt, in conscious rats, BV began to decrease. Peak reduction of -0.22 +/- 0.03 ml/100 g(More)
Changes in blood volume (BV) and Na+ concentration of plasma ([Na+]) were measured continuously during recovery from thermal dehydration in rats. At least 5 days prior to the experiments rats were cannulated into both the jugular vein and the descending aorta. After thermal dehydration (DBT: 36 degrees C, RH: 20%) amounting to approximately 6% of body wt,(More)
Seven rats were exposed to a hot environment (36 degrees C) for about 5 h to induce thermal dehydration. They were allowed to recover from their fluid loss; both tap water and 1.8% NaCl solution were provided simultaneously as drinking fluids. In the recovery stage, these animals initially consumed low NaCl solution (about 41 mEq/l) for the first 90 min and(More)