Eitan Hirsh

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MOTIVATION Data on protein-protein interactions (PPIs) are increasing exponentially. To date, large-scale protein interaction networks are available for human and most model species. The arising challenge is to organize these networks into models of cellular machinery. As in other biological domains, a comparative approach provides a powerful basis for(More)
1 3.1 Low level analysis of microarrays 3.1.1 Introduction This course deals with High level analysis of data gathered by microarrays. Different types of High level analysis include: • (Bi-)Clustering • Reconstruction of transcriptional networks • Induction of classification rules All of these high level analysis methods are based on the same raw data-A(More)
As we studied in our first lecture, each cell contains a copy of the whole gene. But we have many tissues that are constructed of different cells, that are responsible for various tasks. Thus, each cell utilizes only a subset of its genes. Most genes are highly regulated their expression is limited to specific tissues, developmental stages, physiological(More)
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