Eilise Ryan

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The levels of iron (Fe), copper (Cu), zinc (Zn) and potassium (K) have been measured in normal and malignant liver and kidney tissue using X-ray fluorescence. Zn was reduced in liver and kidney tumours by 63% and 26%, respectively. Fe, Cu and K were increased in kidney tumours by 150%, 8% and 90%, and reduced in liver tumours by 76%, 29% and 43%. A(More)
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: does video-assisted thoracic surgery provide a safe alternative to conventional techniques in patients with limited pulmonary function who are otherwise suitable for lung resection? Altogether, more than 280 papers were found using the(More)
Fully activated innate immune cells are required for effective responses to infection, but their prompt deactivation and removal are essential for limiting tissue damage. Here, we have identified a critical role for the prolyl hydroxylase enzyme Phd2 in maintaining the balance between appropriate, predominantly neutrophil-mediated pathogen clearance and(More)
Metabolism of 8-naphthoflavone (BNF) and a-naphthoflavone (ANF) by liver microsomes from control and treated rats, as well as by a purified cytochrome P-450 system, has been investigated. Liver microsomes from control and phenobarbital-treated rats metabolized BNF mainly to 8-hydroxy-BNF, whereas the tmns-7,8dihydrodiol was the major metabolite formed by(More)
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