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  • Deanna N Edwards, Verra M Ngwa, +5 authors Junya Chen
  • Biology, Medicine
  • Science Signaling
  • 2017 (First Publication: 5 December 2017)
  • Malignant tumors reprogram cellular metabolism to support cancer cell proliferation and survival. Although most cancers depend on a high rate of aerobic glycolysis, many cancer cells also displayContinue Reading
  • Eileen Shiuan, Shan Wang, Ariel L. Raybuck, Mark R Boothby, Jin Chen
  • Medicine
  • 2018 (First Publication: 1 September 2018)
  • Despite the advent of targeted therapies and breakthrough immunotherapies, lung cancer remains the number one cause of cancer-related death. Immune checkpoint inhibitors against PD-1 and PD-L1 induceContinue Reading
  • Eileen Shiuan, Wenqiang Song, Simeng Wang, Mark R Boothby, Junye Chen
  • Medicine
  • 2019 (First Publication: 1 July 2019)
  • Background: Given the success of both targeted and immunotherapies against cancer, there is increasing utility for identifying targeted agents that also promote anti-tumor immunity. EphA2 is aContinue Reading
  • Wade T. Iams, Eileen Shiuan, +10 authors Christine M Lovly
  • Medicine
  • Journal of thoracic oncology : official…
  • 2019 (First Publication: 1 November 2019)
  • BACKGROUND Approximately 10% of patients with small cell lung cancer (SCLC) develop a paraneoplastic syndrome (PNS). Neurologic PNS are thought to improve prognosis, which we hypothesized is relatedContinue Reading