Eiko Hidaka

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ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells.

Junya Masumoto, Shinsuke Taniguchi, +7 authors Junko Sagara
The Journal of biological chemistry
1999

The cytoskeletal and/or nuclear matrix molecules responsible for morphological changes associated with apoptosis were identified using monoclonal antibodies (mAbs). We developed mAbs against Triton… (More)

Ras is involved in the negative control of autophagy through the class I PI3-kinase

Shuichi Furuta, Eiko Hidaka, Aya Ogata, Sadaki Yokota, Tohru Kamata
Oncogene
2004

Ras proteins exert a pivotal regulatory function in signal transduction involved in cell proliferation and their activation mutation leads to malignant cell transformation. However, the role of Ras… (More)

Exome sequencing-based identification of mutations in non-syndromic genes among individuals with apparently syndromic features.

Eriko Nishi, Koji Masuda, +8 authors Kosuke Izumi
American journal of medical genetics. Part A
2016

In a clinical setting, the number of organ systems involved is crucial for the differential diagnosis of congenital genetic disorders. When more than one organ system is involved, a syndromic… (More)

Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations.

Kazuyuki Matsuda, Akira Shimada, +19 authors Kenichi Koike
Blood
2007

Of 11 children with juvenile myelomonocytic leukemia (JMML) carrying RAS mutations (8 with NRAS mutations, 3 with KRAS2 mutations), 5 had a profound elevation in either or both the white blood cells… (More)

A case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus.

Shinya Hosaka, N. Nakamura, +7 authors Hideaki Inagaki
Gut
2002

We report a very rare case of primary low grade mucosa associated lymphoid tissue (MALT) lymphoma of the oesophagus. An 83 year old woman was referred to our hospital in June 1999 for further… (More)

Caspy, a zebrafish caspase, activated by ASC oligomerization is required for pharyngeal arch development.

Junya Masumoto, Weibin Zhou, +10 authors Naohiro Inohara
The Journal of biological chemistry
2003

The pyrin domain was identified recently in multiple proteins that are associated with apoptosis and/or inflammation, but the physiological and molecular function of these proteins remain poorly… (More)

A new view of the so-called adenoma malignum of the uterine cervix

Keiko Ishii, Noriko Hosaka, +4 authors T. Katsuyama
Virchows Archiv
1998

Adenoma malignum of the uterine cervix (mucinous type of minimal deviation adenocarcinoma, mucinous MDA), is a unique neoplasm that is difficult to diagnose owing to the deceptively benign… (More)

Use of bone morphogenetic protein 2 and diffusion chambers to engineer cartilage tissue for the repair of defects in articular cartilage.

Masashi Nawata, Shigeyuki Wakitani, +7 authors Kunio Takaoka
Arthritis and rheumatism
2005

OBJECTIVE To examine the ability of cartilage-like tissue, generated ectopically in a diffusion chamber using recombinant human bone morphogenetic protein 2 (rHuBMP-2), to repair cartilage defects in… (More)

Interleukin-6 directly modulates stem cell factor-dependent development of human mast cells derived from CD34(+) cord blood cells.

T. Kinoshita, Naoki Sawai, Eiko Hidaka, T. Yamashita, K. Koike
Blood
1999

In the present study, we attempted to clarify the effects of interleukin-6 (IL-6) on the growth and properties of human mast cells using cultured mast cells selectively generated by stem cell factor… (More)

Immunohistochemical demonstration of alpha1,4-N-acetylglucosaminyltransferase that forms GlcNAcalpha1,4Galbeta residues in human gastrointestinal mucosa.

Mingxin Zhang, Joji Nakayama, +4 authors M. Fukuda
The journal of histochemistry and cytochemistry…
2001

alpha1,4-N-acetylglucosaminyltransferase (alpha4GnT) is a glycosyltransferase that mediates transfer of GlcNAc to betaGal residues with alpha1,4-linkage, forming GlcNAcalpha1--> 4Galbeta-->R… (More)

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