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Alpha-thalassemia is among the world's most common single gene disorders, caused primarily by gene deletions. In Israel, where alpha(o)-trait thalassemia is uncommon, it is of particular importance because of its phenotypic interactions with beta-thalassemia in hetero- and homozygotes. In a study of 232 individuals referred for molecular evaluation of(More)
As reported in the February issue of this journal, over three decades of research suggest that depression is associated with an increased risk of all-cause mortality, although some large recent studies have found negative or null associations. To better inform clinical decision making and evidence-based service provision, it is crucial to resolve this(More)
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