Progressive aggregation of α-synuclein (αS) from pale bodies (PBs) and extension from Lewy neurites (LNs) are candidate mechanisms for Lewy body (LB) formation. To identify how aggregation of αS is related to its extension along neurites, 60-µm-thick brainstem sections of Parkinson disease (PD) patients were prepared for three-dimensional (3D)… (More)
This report presents the results of KINECT applications used in physical rehabilitation tests. Aoyama Gakuin and Kitasato universities collaborated on this project, which is supported by SCOPE. The applications, following standard tests, are for the timed “Up & Go Test”, the timed “10-Meter Walk Test” and for a Joint… (More)
Concomitant deposition of amyloid -beta protein (Aβ) and neuronal tau as neurofibrillary tangles in the human brain is a hallmark of Alzheimer disease (AD). Because these deposits increase during normal aging, it has been proposed that aging brains may also undergo AD-like changes. To investigate the neuropathological changes that occur in the aging primate… (More)
DOCTOR'S EYE is a system for measuring a person's movement without using sensors attached to the body. Its sensing device is KINECT v1. This paper reports basic specifications and the sit-to-stand/stand-to-sit data measured. Recorded data show that DOCTOR'S EYE can be used to measure individual movement characteristics.