Eiichi Tanaka

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The field of nanotechnology holds great promise for the diagnosis and treatment of human disease. However, the size and charge of most nanoparticles preclude their efficient clearance from the body as intact nanoparticles. Without such clearance or their biodegradation into biologically benign components, toxicity is potentially amplified and radiological(More)
OBJECTIVE To analyze the long-term results of distal pancreatectomy with en bloc celiac axis resection (DP-CAR), a newly designed extended surgical procedure for locally advanced cancer of the pancreatic body. SUMMARY BACKGROUND DATA Pancreatic body cancer often involves the common hepatic artery and/or the celiac axis and is regarded as an unresectable(More)
In this paper we propose a new method for correcting zation are described in Section III and in Section IV, garbled words based on Levenshtein distance and weighted Levenrespectively shtein distance. We can correct not only substitution errors, but also insertion errors and deletion errors by this method. According I WEIGHTED LEVENSHTEJN DISTANCE AND to the(More)
OBJECTIVE Our objective was to perform a prospective study of surgical treatment of hilar cholangiocarcinoma according to newly established guidelines for performing safe and curative resections. SUMMARY BACKGROUND DATA The poor survival rate after resection of hilar cholangiocarcinoma is considered to be mainly the result of in-hospital death and(More)
5,10-Methylenetetrahydrofolate reductase (MTHFR), a key enzyme involved in folate metabolism, has two common polymorphisms that affect enzyme activity. The objective of this study was to examine whether there was a correlation between the genotype or haplotype of the MTHFR gene and the efficacy or toxicity of methotrexate (MTX) in the treatment of(More)
Controversy exists over the preferred technique of preoperative biliary drainage (PBD) in patients with hilar cholangiocarcinoma (HCA). The goal of this retrospective study was to identify the preferred technique of PBD for HCA. A total of 128 consecutive patients with HCA diagnosed between September 1999 and December 2009 who underwent PBD were included in(More)
OBJECTIVE To develop and validate a self-administered instrument for measuring functional status in Japanese-speaking rheumatoid arthritis patients. METHODS We translated the Stanford Health Assessment Questionnaire (HAQ) into Japanese (original HAQ), and then made a tentative Japanese version of the HAQ (J-HAQ) with culturally appropriate modifications(More)
Locally advanced cancer of the pancreatic body involving the celiac and/or common hepatic arteries is often considered unresectable. Radical distal pancreatectomy with en bloc resection of these arteries without reconstruction was recently introduced to treat these tumors. However, experience is still limited. This study reviewed the safety and utility of(More)
This paper presents a row-action maximum likelihood algorithm (RAMLA), in which the relaxation parameter is controlled in such a way that the noise propagation from projection data to the reconstructed image is substantially independent of the access order of the input data (subsets) in each cycle of the sub-iterations. The 'subset-dependent' relaxation(More)
To determine the incidence of malignancy and site-specific malignancies in Japanese patients with rheumatoid arthritis (RA). In a prospective large observational cohort study named IORRA, 7,566 patients with RA were enrolled from April 2001 to April 2005 and were followed up to October 2005. Occurrence of malignancy was originally collected by patient(More)