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A classic feature of apoptotic cells is the cell-surface exposure of phosphatidylserine (PtdSer) as an "eat me" signal for engulfment. We show that the Xk-family protein Xkr8 mediates PtdSer exposure… Continue Reading
Background: Xkr8 is essential to scramble phospholipids during apoptosis. The function of other Xkr family members is unknown. Results: Xkr4, Xkr8, and Xkr9 rescued apoptotic lipid scrambling in… Continue Reading
Xk-related protein (Xkr) 8, a protein carrying 10 transmembrane regions, is essential for scrambling phospholipids during apoptosis. Here, we found Xkr8 as a complex with basigin (BSG) or… Continue Reading