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Targeted Skipping of Human Dystrophin Exons in Transgenic Mouse Model Systemically for Antisense Drug Development

• Bo Wu, Ehsan Benrashid, +4 authors Qi Lu
• PloS one
• 2011

Antisense therapy has recently been demonstrated with great potential for targeted exon skipping and restoration of dystrophin production in cultured muscle cells and in muscles of Duchenne Muscular… (More)

Dose-dependent restoration of dystrophin expression in cardiac muscle of dystrophic mice by systemically delivered morpholino

• B. Wu, P. Lu, +4 authors Q L Lu
• Gene Therapy
• 2010

We have earlier shown that antisense morpholino oligomers are able to restore dystrophin expression by systemic delivery in body-wide skeletal muscles of dystrophic mdx mice. However, the levels of… (More)

Guanine Analogues Enhance Antisense Oligonucleotide-induced Exon Skipping in Dystrophin Gene In Vitro and In Vivo.

• Yihong Hu, Bo Wu, +7 authors Qi Long Lu
• Molecular therapy : the journal of the American…
• 2010

Exon skipping has demonstrated great potential for treating Duchenne muscular dystrophy (DMD) and other diseases. We have developed a drug-screening system using C2C12 myoblasts expressing a reporter… (More)

Determining the Optimal Timing for Initiation of Adjuvant Chemotherapy After Resection for Stage II and III Colon Cancer.

• Zhifei Sun, Mohamed Abdelgadir Adam, +4 authors John Migaly
• Diseases of the colon and rectum
• 2016

BACKGROUND Several reports suggest that the efficacy of adjuvant chemotherapy on survival diminishes over time for colon cancer; however, precise timing of its loss of benefit has not been… (More)

Mycotic Saccular Abdominal Aortic Aneurysm in an Infant after Cardiac Catheterization: A Case Report.

• Ehsan Benrashid, Christopher Cameron McCoy, Henry E. Rice, Cynthia E K Shortell, Mitchell Wayne Cox
• Annals of vascular surgery
• 2015

Abdominal aortic aneurysms (AAAs) are a rare entity in the pediatric population. Children with mycotic (infectious) AAA in particular are at risk of life-threatening rupture due to their rapid… (More)

Operative and perioperative management of infected arteriovenous grafts.

• Ehsan Benrashid, Linda M Youngwirth, Leila Mureebe, J Chappell H Lawson
• The journal of vascular access
• 2017

Vascular graft infections are a particularly troublesome complication for dialysis patients, many of whom are in an already immunocompromised state. The objective of this review is to detail the risk… (More)

The utility of the aortic dissection team: outcomes and insights after a decade of experience.

• Nicholas D. Andersen, Ehsan Benrashid, +6 authors G. Chad Hughes
• Annals of cardiothoracic surgery
• 2016

BACKGROUND Mortality rates following acute type A aortic dissection (ATAAD) repair are reduced when operations are performed by a high-volume acute aortic dissection (AAD) team, leading to efforts to… (More)

Laparotomy during endovascular repair of ruptured abdominal aortic aneurysms increases mortality.

• Shaunak Sanjay Adkar, Ryan S. Turley, Ehsan Benrashid, Mitchell Wayne Cox, Leila Mureebe, Cynthia E K Shortell
• Journal of vascular surgery
• 2017

OBJECTIVE Subset analyses from small case series suggest patients requiring laparotomy during endovascular repair of ruptured abdominal aortic aneurysms (REVAR) have worse survival than those… (More)

Evolving practice pattern changes and outcomes in the era of hybrid aortic arch repair.

• Ehsan Benrashid, Hanghang Wang, +4 authors G. Chad Hughes
• Journal of vascular surgery
• 2016

OBJECTIVE The role of hybrid repair in the management of aortic arch pathology, and long-term outcomes with these techniques, remains uncertain. We report a decade of experience with hybrid arch… (More)

Pulmonary Valve Replacement With a Trifecta Valve Is Associated With Reduced Transvalvular Gradient.

• Brian C H Gulack, Ehsan Benrashid, Robert D. B. Jaquiss, Andrew J. Lodge
• The Annals of thoracic surgery
• 2017

BACKGROUND Outcomes after surgical pulmonary valve replacement (PVR) in patients with congenital cardiac disease are limited by long-term valve deterioration, which may be hastened by turbulent flow.… (More)

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