Eg Caiani

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BACKGROUND Echocardiographic contrast media have been used to assess myocardial perfusion and to enhance endocardial definition for improved assessment of left ventricular (LV) function. These methodologies, however, have been qualitative or have required extensive offline image analysis. Power modulation is a recently developed imaging technique that(More)
We tested the feasibility of real-time three-dimensional (3D) echocardiographic (RT3DE) imaging to measure left heart volumes at different gravity during parabolic flight and studied the effects of lower body negative pressure (LBNP) as a countermeasure. Weightlessness-related changes in cardiac function have been previously studied during spaceflights(More)
OBJECTIVE To develop a technique for volumetric analysis of real time three dimensional echocardiography (RT3DE) data aimed at quantifying left ventricular (LV) mass and to validate the technique against magnetic resonance (MR) assumed as the reference standard. DESIGN RT3DE, which has recently become widely available, provides dynamic pyramidal data(More)
Tissue Doppler is used to evaluate mitral annulus (MA) dynamics. This technique has two major limitations: it is two-dimensional and angle-dependent. To solve these limitations, our aim was to develop and test a tool for automated 3D tracking and quantification of the MA motion throughout the cardiac cycle by using real-time 3D echocardiography (RT3DE). The(More)
Right ventricular (RV) volume quantification from cardiac magnetic resonance imaging is based on manual tracing of endocardial boundaries and application of geometric modeling. This procedure is subjective, time-consuming and may bias volume measurements since the right ventricle is a complex structure that is not well suited to a geometric model. We(More)
Mitral valve (MV) physiopathological function and the effects of surgical repair can be studied through finite element models (FEMs). However, this approach assumes idealized morphology and boundary conditions limiting the analysis to paradigmatic scenarios and precluding patient-specific surgical planning. To overcome this limitation, we integrated into a(More)
We aimed at developing and testing an automated method for motion artifacts compensation, to reduce potential misalignment between short-axis (SAX) and two-and four-chamber long-axis (2ch4chLAX) cardiac magnetic resonance (CMR) images that could introduce artifacts in advanced 3D volumetric analysis, thus precluding accurate measurements. Each SAX slice of(More)
Parabolic flight (PF) elicits changes in hydrostatic pressure gradients, resulting in increase (at 0Gz) or decrease (at 1.8Gz) in cardiac preload. The magnitude of these changes on left ventricular (LV) and atrial (LA) volumes, as well as on myocardial velocities, strain and strain rates, is largely unknown. Using real-time 3D (RT3DE) and Doppler tissue(More)
Ballistocardiography (BCG) is a non-invasive technique which measures the acceleration of a body induced by cardiovascular activity, namely the force exerted by the beating heart. Measuring a BCG in a gravity-free environment provides ideal conditions where the subject is completely decoupled from its environment. Furthermore, because gravity constrains the(More)
Cardiac magnetic resonance imaging (CMRI) is the standard for estimates of LV volumes, ejection fraction and mass. These computations are based on extensive manual tracing of endocardial and epicardial borders and are subjective and time-consuming. We developed a new technique for semi-automated surface detection for the measurement of LV end-systolic and(More)