Eeva Leinonen

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OBJECTIVE Apolipoprotein CIII (apoCIII) is an independent risk factor for cardiovascular disease, but the molecular mechanisms involved are poorly understood. We investigated potential proatherogenic properties of apoCIII-containing LDL from hypertriglyceridemic patients with type 2 diabetes. RESEARCH DESIGN AND METHODS LDL was isolated from control(More)
This study investigates, within the theory of relevance of Sperber & Wilson (1995), how3-, 4-, and 5-year-old children (n = 45) use context when answering questions. The children were required to answer questions that placed differing contextual and processing demands on them, as predicted by the theory. The results indicate that an increasing ability to(More)
This thesis contributes to the field of collaborative information systems and Computer-Supported Cooperative Work (CSCW). It extends the notion of technological support for design activities "in use" beyond providing the flexibility to tailor collaborative software, to provide means to support the appropriation process of these tools in their application(More)
Utilizing relevance theory, this study investigated the ability of children with Asperger syndrome (AS) and high-functioning autism (HFA) to use context when answering questions and when giving explanations for their correct answers. Three groups participated in this study: younger AS/HFA group (age 7-9, n=16), older AS/HFA group (age 10-12, n=23) and a(More)
BACKGROUND Pragmatic language impairment in children with specific language impairment has proved difficult to assess, and the nature of their abilities to comprehend pragmatic meaning has not been fully investigated. AIMS To develop both a cognitive approach to pragmatic language assessment based on Relevance Theory and an assessment tool for identifying(More)
The present study investigates children's syntactic and pragmatic processing when specifying referents presented in short video clips. Within Relevance theory, the assumption of 'optimal relevance' implies that utterances are intended to involve the least processing effort on the part of the listener. In the present context, lexically specified NPs are(More)
Three groups of language-normal (LN) 6, 8 and 16/17 year olds, and a group of language-impaired (LI) children were given a task answering questions about pictures that involved inferential meaning. A developmental progression in the types of responses given is seen, with the LI children performing like the youngest LN children. A similar progression is seen(More)
OBJECTIVE Although fenofibrate was associated with less progression of albuminuria in the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study, it is unknown if it has any effect on renal function. We explored if there were changes in commonly available markers of renal function during fenofibrate treatment in the FIELD Helsinki cohort(More)
  • Mary Thornton, Amanda Jefferies, Indra Jones, Jon Alltree, Eeva Leinonen
  • 2008
The University of Hertfordshire " s Managed Learning Environment initiative, known as StudyNet, was developed in-house. Throughout the development, the enhancement of learning and teaching quality has remained a central tenet. However, take up has been extremely variable. This research, through questionnaire survey, sought to assess the extent of StudyNet(More)
A global increase in aging population, combined with a growing number of people with dementia, creates new challenges to develop guiding technology for people with memory disturbances in their daily activities. In this study we have tested the prototype of a wayfinding aid using predefined routes. The orientation advice was given through three modalities,(More)