Edward W. Thommes

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BACKGROUND The natural (i.e. unvaccinated population) attack rate of an infectious disease is an important parameter required for understanding disease transmission. As such, it is an input parameter in infectious disease mathematical models. Influenza is an infectious disease that poses a major health concern worldwide and the natural attack rate of this(More)
Author's response to reviews: Thank you for the additional comments, copied below with responses:-Was any ethical approval or permission to access data sources obtained for the study? Please provide details if so. ==> No, all data was from published sources Please move the details on funding to the Acknowledgements section. ==> moved-Throughout the(More)
BACKGROUND The adoption of quadrivalent influenza vaccine (QIV) to replace trivalent influenza vaccine (TIV) in immunization programs is growing worldwide, thus helping to address the problem of influenza B lineage mismatch. However, the price per dose of QIV is higher than that of TIV. In such circumstances, cost-effectiveness analyses provide important(More)
Trivalent inactivated influenza vaccines (IIV3s) protect against 2 A strains and one B lineage; quadrivalent versions (IIV4s) protect against an additional B lineage. The objective was to assess projected health and economic outcomes associated with IIV4 versus IIV3 for preventing seasonal influenza in the US. A cost-effectiveness model was developed to(More)
This research investigates improvement in personal efficiency of a driver based on the driver behaviour on a generic three-lane highway in Ontario. The behaviour is classified in: Law-Abiding drivers, opportunistic Deviant drivers, cautious Non-Myopic drivers, tailgating Aggressive drivers, and ambivalent Imitator drivers. For each driver in a class, the(More)
We examine a pricing game between firms that produce differentiated products and in which consumer preferences evolve in response to the market shares of the available products. One of the products is new and a subset of consumers (early adopters) have a relatively strong preference for it, while the remaining consumers are influenced by the relative market(More)
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