• Publications
  • Influence
Diabetes mellitus, CYP2C19 genotype, and response to escalating doses of clopidogrel. Insights from the ELEVATE-TIMI 56 Trial.
Both diabetes mellitus (DM) and carriage of the CYP2C19*2 allele are associated with a reduced response to clopidogrel. The relative contributions of these factors and whether higher clopidogrelExpand
  • 12
  • 1
Balancing Antiplatelet and Anticoagulant Therapies in Patients with Cardiovascular Disease
Anticoagulation is needed for stroke prevention in patients with atrial fibrillation. Antiplatelet therapy is essential for the prevention of stent thrombosis and the reduction of cardiovascularExpand
  • 2
  • 1
Antithrombotic therapy: triple therapy or triple threat?
Antithrombotic therapy plays an essential role in the management of some of the most common and morbid medical conditions. Triple oral antithrombotic therapy (TOAT) is defined as the administrationExpand
  • 11
Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement
To assess the impact of low flow with and without preserved left ventricular ejection fraction (LVEF) on outcomes after transcatheter aortic valve replacement (TAVR).
  • 8
Role of Oral Anticoagulants in Patients After an Acute Coronary Syndrome
After an acute coronary syndrome, patients continue to be at risk of adverse cardiovascular events despite treatment with the current standard of antithrombotic therapy. The risk may be in partExpand
  • 8
  • PDF
Dual antiplatelet therapy for heart disease.
Within the body, the heart pumps blood through paths called vessels so that all of the body’s organs get the oxygen and nutrients they need to function properly. The blood itself contains manyExpand
  • 4
  • PDF
Acute Coronary Syndrome in a 52-Year-Old Woman With Scleroderma
Information about a real patient is presented in stages (boldface type) to expert clinicians (Drs Mauri and Dr MacRae), who respond to the information, sharing their reasoning with the readerExpand
  • 1
  • PDF