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- Edward S. Ruthazer, Colin J. Akerman, Hollis T. Cline
- Science
- 2003
To determine how patterned visual activity regulates the development of axonal projections, we collected in vivo time-lapse images of retinal axons from albino Xenopus tadpoles in which binocular… (More)
- Edward S. Ruthazer, Michael P. Stryker
- The Journal of neuroscience : the official…
- 1996
Horizontal connections in area 17 of adult cats and ferrets link cells with similar preferred orientations by a patchy network of projections extending several millimeters across the cortex. The… (More)
- Edward S. Ruthazer, Jianli Li, Hollis T. Cline
- The Journal of neuroscience : the official…
- 2006
The developmental refinement of topographic projections in the brain is reflected in the dynamic sculpting of axonal arbors that takes place as connections between CNS structures form and mature. To… (More)
- Edward S. Ruthazer, Hollis T. Cline
- Journal of neurobiology
- 2004
The development of orderly topographic maps in the central nervous system (CNS) results from a collaboration of chemoaffinity cues that establish the coarse organization of the projection and… (More)
- Onkar S. Dhande, Ethan W. Hua, +6 authors Michael C. Crair
- The Journal of neuroscience : the official…
- 2011
The maturation of retinal ganglion cell (RGC) axon projections in the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC) relies on both molecular and activity-dependent… (More)
Ocular dominance peaks at pinwheel center singularities of the orientation map in cat visual cortex.
- Michael C. Crair, Edward S. Ruthazer, Deda C. Gillespie, Michael P. Stryker
- Journal of neurophysiology
- 1997
In the primary visual cortex of monkey and cat, ocular dominance and orientation are represented continuously and simultaneously, so that most neighboring neurons respond optimally to visual… (More)
- Jianzhong Z Jin, Chong Weng, +5 authors Jose-Manuel Alonso
- Nature Neuroscience
- 2008
On- and off-center geniculate afferents form two major channels of visual processing that are thought to converge in the primary visual cortex. However, humans with severely reduced on responses can… (More)
- Naofumi Uesaka, Satoshi Hirai, Takuro Maruyama, Edward S. Ruthazer, Nobuhiko Yamamoto
- The Journal of neuroscience : the official…
- 2005
The influence of neuronal activity on cortical axon branching was studied by imaging axons of layer 2/3 neurons in organotypic slice cultures of rat visual cortex. Upper layer neurons labeled by… (More)
The significance of functional maps for cortical plasticity was investigated by imaging of intrinsic optical signals together with single-unit recording in kittens. After even a brief period of… (More)
- Katherine E Horn, Stephen D. Glasgow, +15 authors Timothy E Kennedy
- Cell reports
- 2013
The transmembrane protein deleted in colorectal cancer (DCC) and its ligand, netrin-1, regulate synaptogenesis during development, but their function in the mature central nervous system is unknown.… (More)