Edward S. Mason

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There is increasing evidence that dysregulated immune responses play key roles in the pathogenesis and complications of type 1 but also type 2 diabetes. Indeed, chronic inflammation and autoimmunity, which are salient features of type 1 diabetes, are now believed to actively contribute to the pathogenesis of type 2 diabetes. The accumulation of activated(More)
Type 1 diabetes (T1D) occurs through a breakdown of self-tolerance resulting in the autoimmune destruction of the insulin producing β-islets of the pancreas. A numerical and functional waning of CD4+ Foxp3+ regulatory T (Treg) cells, prompted by a pancreatic IL-2 deficiency, accompanies Th1 autoimmunity and T1D progression in non-obese diabetic (NOD) mice.(More)
  • E S Mason
  • 1995
The competing hypotheses of socialization, structural, and social role theories were used to investigate the possible existence of gender differences in job satisfaction. The hypotheses were tested in a sample of over 13,000 U.S. employees from approximately 130 organizations and divisions across a variety of industries. The organizations were clients of a(More)
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