Edward S. Cooper

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OBJECTIVE The purposes of this study were to evaluate the oxygen affinity of hemoglobin (Hb) in healthy retired racing Greyhounds via cooximetry, and to establish reference intervals for blood gases and cooximetry in this breed. DESIGN Prospective clinical study. SETTING University Teaching Hospital. ANIMALS Fifty-seven Greyhounds and 30 non-Greyhound(More)
BACKGROUND It is well established that hematocrit (Hct) influences whole blood thromboelastography (TEG) tracings. Previous studies showed hypercoagulable TEG tracings in anemic patients despite clinical expectations that anemia often prolongs bleeding. TEG is a viscoelastic assessment of clot kinetics, and Hct is the main determinant of whole blood(More)
OBJECTIVE To discuss areas of differing opinion in the management of feline urethral obstruction and present current evidence to either support or refute common practices. ETIOLOGY Urethral obstruction may occur as a result from a functional obstruction (idiopathic obstruction) or a physical obstruction, such as mucous plugs or calculi within the urethra.(More)
Bronchoalveolar lavage (BAL) is considered to be a safe procedure in humans and other animals. However, in some instances, potentially life-threatening complications can arise. In this clinical report, a dog with eosinophilic airway disease that underwent a BAL and subsequently became profoundly dyspneic during the recovery period is described. The dyspnea(More)
OBJECTIVE To directly assess microcirculatory changes associated with induced hemorrhagic shock by use of sidestream dark field microscopy (SDM) and correlate those values with concurrently measured macrovascular and blood gas variables in healthy anesthetized dogs. ANIMALS 12 adult dogs. PROCEDURES Dogs were anesthetized and splenectomized.(More)
A 12-year-old, neutered male, mixed-breed dog was presented to The Ohio State University Veterinary Teaching Hospital with a history of weight loss and weakness. Laboratory abnormalities reported by the referring veterinarian during the past year included increased alkaline phosphatase (ALP) activity, hyperalbuminemia, and nonregenerative anemia. On(More)
Objectives. To explore: 1) the relationship between plasma insulin-like growth factor-1 (IGF-1) and other markers of growth; and 2) the effect of serum concentrations of tumor necrosis factor a (TNF) on growth variables in children (2–10 years) stunted by Trichuris dysentery syndrome (TDS), recovering cases, and their matched controls. Method. Fourteen(More)
OBJECTIVE To describe the use of glucagon infusion for adjunctive treatment of hypoglycemia in dogs. DESIGN Multicenter retrospective case series. SETTING One university and 1 private veterinary referral hospital. ANIMALS Dogs were included if they were hospitalized and received glucagon therapy for hypoglycemia, defined as blood glucose concentration(More)
OBJECTIVE To describe the clinical presentation and successful treatment of a dog that ingested a lethal dose (approximately 330 mg/kg) of 5-fluorouracil (5-FU). CASE SUMMARY A 1-year-old male intact German Shepherd dog was presented to the Emergency Service of the Ohio State University Veterinary Medical Center after ingesting 10 g of 5% 5-FU cream. The(More)
OBJECTIVES To determine the frequency of delayed postoperative bleeding in retired racing Greyhounds with appendicular bone tumors undergoing limb amputations. To identify if administration of epsilon-aminocaproic acid (EACA) was effective on the prevention of postoperative bleeding. DESIGN Retrospective study from December 2003 to December 2008. (More)