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Endothelial cells in vivo are continuously exposed to shear stress, a tangential force generated by the flow of blood across their apical surfaces that affects endothelial cell structure and function. By contrast, the Transwell apparatus cannot reproduce the presence of intraluminal blood flow that is essential for the formation and differentiation of the(More)
Active and passive tobacco smoke are associated with the dysfunction of endothelial physiology and vascular impairment. Studies correlating the effects of smoking and the brain microvasculature at the blood-brain barrier (BBB) level have been largely limited to few selective compounds that are present in the tobacco smoke (TS) yet the pathophysiology of(More)
Repetitive traumatic brain injury (rTBI) is one of the major risk factors for the abnormal deposition of phosphorylated tau (PT) in the brain and chronic traumatic encephalopathy (CTE). CTE and temporal lobe epilepsy (TLE) affect the limbic system, but no comparative studies on PT distribution in TLE and CTE are available. It is also unclear whether PT(More)
PURPOSE OF THE STUDY X-ray measurements of the proximal tibial slope only study bony structures, without considering cartilage and meniscil thickness. It is well known that the posterior horn of the meniscil is thicker than the anterior one, and this could decrease the bony postero-distal slope. The aim of this study was to measure the meniscal slope,(More)
The aim of this study is to describe the microvascularisation of the raphe buccalis located at the inner surface of the cheek. The raphe buccalis is the zone where the maxillary and mandibulary prominences fuse in the embryo during the second month of life. This study was conducted using heads from edentulous subjects, fetuses, newborns and adults, injected(More)
The relative carpal weights (Weight of each of the eight carpal bones/Weight of the complete carpus x 100) were studied in a series of 95 complete human adult carpi (dried bones). The greatest was the capitatum (19.92%; mean rank 1.16) and the smallest the pisiform (4.43%; mean rank 8.00). The scaphoideum and the hamatum presented very near values (17.19(More)
The aim of this study is to verify the aperture or the closure of the renal space. The study is undertaken on histological sections of fetuses in the horizontal and sagittal planes. On each side, the kidney and the suprarenal gland are disposed in a space that is closed on all sides. The anterior and posterior layers of the renal fascia fuse at the upper(More)
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