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Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction.

• Edward P. Carter, Abbie E. Fearon, R P Grose
• Trends in cell biology
• 2015

Since its discovery 40 years ago, fibroblast growth factor (FGF) receptor (FGFR) signalling has been found to regulate fundamental cellular behaviours in a wide range of cell types. FGFRs regulate… (More)

A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer

• Edward P. Carter, James A. Gopsill, Jennifer. J. Gomm, J. Louise Jones, R P Grose
• Breast Cancer Research
• 2017

3D modelling fulfils a critical role in research, allowing for complex cell behaviour and interactions to be studied in physiomimetic conditions. With tissue banks becoming established for a number… (More)

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer

• Abbie E. Fearon, Edward P. Carter, +16 authors R P Grose
• Cell reports
• 2018

Development of resistance causes failure of drugs targeting receptor tyrosine kinase (RTK) networks and represents a critical challenge for precision medicine. Here, we show that PHLDA1… (More)

Fibroblast growth factor-mediated crosstalk in cancer etiology and treatment.

• Natasha S. Clayton, Abigail S Wilson, E P Laurent, R P Grose, Edward P. Carter
• Developmental dynamics : an official publication…
• 2017

It is becoming increasingly evident that multiple cell types within the tumor work together to drive tumour progression and impact on both the response to therapy and the dissemination of tumour… (More)

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