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  • A V Vasiliskov, Edward N Timofeev, Sergey A Surzhikov, Alexei L. Drobyshev, V V Shick, A. D. Mirzabekov
  • Medicine, Biology
  • BioTechniques
  • 1999 (First Publication: 1 September 1999)
  • The manufacturing of microchips containing oligonucleotides and proteins immobilized within gel pads, ranging in size from 10 x 10 to 100 x 100 microns, is described. The microchips are produced byContinue Reading
  • Anna Varizhuk, Vladimir B. Tsvetkov, +9 authors Galina E. Pozmogova
  • Chemistry, Medicine
  • European journal of medicinal chemistry
  • 2013 (First Publication: 1 September 2013)
  • A series of DNA aptamers bearing triazole internucleotide linkages that bind to thrombin was synthesized. The novel aptamers are structurally analogous to the well-known thrombin-inhibitingContinue Reading
  • Vladimir B. Tsvetkov, Anna Varizhuk, Galina E. Pozmogova, Igor P. Smirnov, Natalia A. Kolganova, Edward N Timofeev
  • Chemistry
  • Scientific Reports
  • 2015 (First Publication: 17 November 2015)
  • In this study we describe new modified analogs of the thrombin binding aptamer (TBA) containing 5-nitroindole residues. It has been shown that all modified TBAs form an anti-parallel G-quadruplexContinue Reading