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Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity.
lin-4 and let-7 are founding members of an extensive family of genes that produce small transcripts, termed microRNAs (miRNAs). In Caenorhabditis elegans, lin-4 and let-7 control the timing ofExpand
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The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster.
In Caenorhabditis elegans, the heterochronic pathway controls the timing of developmental events during the larval stages. A component of this pathway, the let-7 small regulatory RNA, is expressed atExpand
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GENE-ENZYME VARIATION IN THREE SYMPATRIC SPECIES OF LITTORINA. II. THE ROSCOFF POPULATION, WITH A NOTE ON THE ORIGIN OF NORTH AMERICAN L. LITTOREA
Gene-enzyme variation was examined at ten to fifteen loci in three sympatric species of Littorina collected from Cape Cod, Massachusetts and Roscoff, Brittany. The North American and FrenchExpand
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GENE-ENZYME VARIATION IN THREE SYMPATRIC SPECIES OF LITTORINA
Gene-enzyme variation was examined, electrophoretically, at three non-specific esterase loci in 15 sympatric populations of the prosobranch gastropods: Littorina littorea L. obtusata, and L.Expand
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Heterosis and the Maintenance of Enzyme Polymorphism
An attempt is made to synthesize and evaluate the available evidence suggesting that single- and multiple-locus heterosis is an important mechanism in maintaining gene-enzyme polymorphism in nature.Expand
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The juvenile hormone analogue, methoprene, inhibits ecdysterone induction of small heat shock protein gene expression.
The small heat shock protein (hsp) genes of Drosophila are expressed in cultured cells in response to the moulting hormone, ecdysterone. We show here that juvenile hormone (JHIII) and the juvenileExpand
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Ecdysterone regulatory elements function as both transcriptional activators and repressors.
A synthetic, 23-bp ecdysterone regulatory element (EcRE), derived from the upstream region of the Drosophila melanogaster hsp27 gene, was inserted adjacent to the herpes simplex virus thymidineExpand
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The isolation of two juvenile hormone-inducible genes in Drosophila melanogaster.
Juvenile hormone (JH) is an important regulator of both insect development and reproductive maturation. Although the molecular mechanism of JH action is not yet known, there is growing circumstantialExpand
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Juvenile hormone regulation of the E75 nuclear receptor is conserved in Diptera and Lepidoptera.
Despite longstanding efforts, the juvenile hormone (JH) signaling pathway remains unknown. In Drosophila melanogaster (Diptera), JH activates expression of the E75A nuclear receptor. The E75 geneExpand
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