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Assembling structures to divide space controllably and spontaneously into subunits at the nanometer scale is a significant challenge, although one that biology has solved in two distinct ways: prokaryotes and eukaryotes. Prokaryotes have a single compartment delimited by one or more lipid-protein membranes. Eukaryotes have nested-membrane structures that(More)
Chemical permeation enhancers can permeabilize the human skin to enable transdermal delivery of drugs, but their use is often limited by the accompanying skin irritation. Novel chemical enhancer combinations based on synergistic interactions amongst their components have the potential to address this limitation. However, discovery of such combinations(More)
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