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OBJECTIVE To determine if the intraoperative rapid parathyroid hormone (PTH) assay can be used to accurately predict postoperative calcium levels following total or completion thyroidectomy. DESIGN A prospective study. SETTING Tertiary care referral center. PATIENTS One hundred four patients following a total or completion thyroidectomy.Intervention(More)
BACKGROUND In the present study, we assessed the relationship of serum insulin levels and risk of recurrence in men with localized prostate cancer because of the relationship of insulin to the development of prostate cancer, and because insulin is a growth factor. METHODS Participants in our study were found through urology and radiation oncology clinics,(More)
Non-polar extracts of sera from human males contain immunoreactive testosterone in a form that is released by mild alkaline hydrolysis. The non-polar derivative shows no immunoreactivity with testosterone antibody prior to hydrolysis. Hydrolyzed non-polar serum extracts from ten adult male volunteers contained 2.0 +/- 0.8 (SD) ng/mL of testosterone. Neither(More)
OBJECTIVE To examine the role of intraoperative rapid parathyroid hormone (PTH) monitoring in the surgical management of hyperparathyroidism. DESIGN Thirty-eight-month retrospective review. SETTING Tertiary care academic medical center. PATIENTS One hundred consecutive patients undergoing surgery for primary hyperparathyroidism. INTERVENTION All(More)
Respiratory observations made during nutritive feeding and a complete daytime nap within the first week of life on ten newborns who subsequently were victims of sudden infant death syndrome (SIDS) were compared with normative data based on 1,301 infants of comparable ages. Measurements were obtained of all apneic pauses and/or transient respiratory(More)
The later stages of cochlear differentiation and the developmental onset of hearing require thyroid hormone. Although thyroid hormone receptors (TRs) are a prerequisite for this process, it is likely that other factors modify TR activity during cochlear development. The mouse cochlea expresses type 2 deiodinase (D2), an enzyme that converts thyroxine, the(More)
In order to investigate possible contamination of saliva samples with formula or breast milk obtained from young infants for cortisol assays, we measured cortisol concentrations in 3 common infant milk formulas and in breast milk before and after defatting and extraction using a commercial radioimmunoassay kit. Cortisol concentrations obtained prior to(More)
UNLABELLED Triiodothyronine is the active thyroid hormone produced by de-iodination of the precursor thyroxine that is necessary for the growth of prostate cancer cells in vitro. For this reason we assessed serum triiodothyronine levels in men with localized prostate cancer, benign prostatic hyperplasia (BPH) and controls in the same age group. MATERIALS(More)
The effects of metabolic acidosis upon the pattern of apnea during sleep were assessed in ten sleep apnea patients. Four had pure obstructive apnea, two pure central apnea, and four had mixed apnea. Acidosis was induced with acetazolamide. Acid-base shifts had little effect in pure obstructive and pure central apnea, but had a significant effect in mixed(More)