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This study sought to determine the relationship between behavioral disturbance and functional status in a longitudinally studied sample of patients with Alzheimer's disease (AD). One hundred and forty-nine patients meeting NINCDS-ADRDA criteria for probable AD were followed for an average of 37.3 months, with follow-up assessments every 6 months. Subjects(More)
Eighty patients admitted to a specialized alcohol detoxification unit, who had blood alcohol levels of .15% or less and were not currently intoxicated, participated in a double-blind trial involving treatment with either halazepam or chlordiazepoxide. A flexible dosage schedule was followed for 5 days with the objective of using the largest dose on the(More)
Forty alcoholics without other significant medical or psychiatric problems were studied on a research ward for two weeks. All subjects abstained from alcohol and cigarettes during the first week; 30 randomly selected subjects were permitted unlimited alcohol and/or cigarettes during the second week. Plasma testosterone levels were normal during the first(More)
The purpose of this study was to assess the occurrence of brain atrophy in alcoholic patients as measured by two methods--psychological testing and CAT scanning. The study focused upon the relationships between gross cerebral atrophy and two variables which are considered to be major determinants in the development of brain damage. The variables are (1) the(More)
In the light of the fact that ethyl alcohol can cause damage to the brain, especially in the area of motor control, a study of the incidence of alcohol-related neuropsychological impairment in individuals arrested for driving while intoxicated (DWI) would be of great value. The authors report on 100 DWI offenders given a Memory-for Designs Test: 33% of the(More)
OBJECTIVE The purpose of this study was to examine the behavioural and cognitive effects of selegiline in a group of moderately behaviourally disturbed AD patients. DESIGN This was a 14-week randomized double-blind placebo-controlled study of selegiline (10 mg) and placebo. SETTING An outpatient clinic in an urban-based tertiary referral centre in the(More)
Adolf Beck, born in 1863 at Cracow (Poland), joined the Department of Physiology of the Jagiellonian University in 1880 to work directly under the supervision of the prominent physiology professor, Napoleon Cybulski. Following his suggestion, Beck started experimental studies on the electrical brain activity of animals, especially in response to sensory(More)
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