Edward Chang

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We describethe Stanford Temporal Prover (STEP), a system being developed to support the computer-aided formal verification of concurrent and reactive systems based on temporal specifications. Unlike systems ba_ed on model-checking,STeP is not restricted to finite-state systems. It combines mode/cAse/ringand deductive rn_tho_ to ¢llow the verification of R(More)
Pyrrolysine is the 22nd amino acid. An unresolved question has been how this atypical genetically encoded residue is inserted into proteins, because all previously described naturally occurring aminoacyl-tRNA synthetases are specific for one of the 20 universally distributed amino acids. Here we establish that synthetic L-pyrrolysine is attached as a free(More)
Mutations in the MAPT gene encoding tau protein lead to neurofibrillary lesion formation, neurodegeneration, and cognitive decline associated with frontotemporal lobar degeneration. While some pathogenic mutations affect MAPT introns, resulting in abnormal splicing patterns, the majority occur in the tau coding sequence leading to single amino acid changes(More)
ii I certify that I have read this dissertation and that in my opinion it is fully adequate, in scope and in quality, a s a dissertation for the degree of Doctor of Philosophy. Zohar Manna Principal Adviser I certify that I have read this dissertation and that in my opinion it is fully adequate, in scope and in quality, a s a dissertation for the degree of(More)
Suture techniques are an indispensable means to biologically sculpt the cartilage of the nose. Here the authors review their use in tip-plasty and present a 4-suture algorithm that allows for simple, complete control in sculpting the shape of all nasal tips in primary rhinoplasty. After a standard cephalic trim of the lateral crus leaving it 6 mm wide, one(More)