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The costs to the NHS of multiple births after IVF treatment in the UK.

• William Leigh Ledger, Dilly O C Anumba, Neil Marlow, Christine M. Thomas, Edward C F Wilson
• BJOG : an international journal of obstetrics and…
• 2006

OBJECTIVES To determine the cost to the NHS resulting from multiple pregnancies arising from IVF treatment in the UK, and to compare those costs with the cost to the NHS due to singleton pregnancies… (More)

Leukotriene antagonists as first-line or add-on asthma-controller therapy.

• David J Price, Stanley D. Musgrave, +13 authors Ian Harvey
• The New England journal of medicine
• 2011

BACKGROUND Most randomized trials of treatment for asthma study highly selected patients under idealized conditions. METHODS We conducted two parallel, multicenter, pragmatic trials to evaluate the… (More)

Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: a randomised controlled trial.

• Ludmila Shulgina, Anthony P. Cahn, +8 authors Andrew M Wilson
• Thorax
• 2013

BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a fatal condition with limited treatment options. However, in a previous small study, co-trimoxazole was found to be beneficial. METHODS In a… (More)

Home-based medication review in older people: is it cost effective?

• Margaret Pacini, Richard J Smith, Edward C F Wilson, Richard Holland
• PharmacoEconomics
• 2007

BACKGROUND Medication review by pharmacists is increasingly being implemented in the primary care setting and has been incorporated into the new pharmacy contract in the UK. This study aims to… (More)

Are brief interventions to increase physical activity cost-effective? A systematic review

• Vijay S Gc, Edward C F Wilson, Marc Suhrcke, Wendy Hardeman, Stephen Sutton
• British journal of sports medicine
• 2016

OBJECTIVE To determine whether brief interventions promoting physical activity are cost-effective in primary care or community settings. DESIGN Systematic review of economic evaluations. METHODS… (More)

Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting.

• Razelle Kurzrock, Hagop M Kantarjian, +7 authors Saïd M. Sebti
• Blood
• 2003

R115777 is a potent farnesyltransferase (FTase) inhibitor with substantial antitumor activity in preclinical models. We conducted a phase 1 study (3 + 3 design) of R115777 in patients with… (More)

Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple…

• M. Sabes Alsina, Rafael Fonseca, +15 authors Saïd M. Sebti
• Blood
• 2004

Patients with multiple myeloma (MM) with mutated RAS are less likely to respond to chemotherapy and have a shortened survival. Therefore, targeting RAS farnesylation may be a novel approach to… (More)

Homicide or suicide: the killing of suicidal persons by law enforcement officers.

• Edward C F Wilson, Joseph H. Davis, Joseph D. Bloom, P J Batten, Sheku G. Kamara
• Journal of forensic sciences
• 1998

This paper presents 15 deaths of suicidal persons in Oregon and Florida who, by their behavior, sufficiently provoked law enforcement officers into killing them. Four deaths were certified as… (More)

Performance of the UKPDS outcomes model for prediction of myocardial infarction and stroke in the ADDITION-Europe trial cohort.

• Libo Tao, Edward C F Wilson, Simon J Griffin, Rebecca K. Simmons
• Value in health : the journal of the…
• 2013

OBJECTIVES We assessed the performance of the UK Prospective Diabetes Study (UKPDS) outcomes model in predicting the risk of myocardial infarction (MI) and stroke in the Anglo-Danish-Dutch Study of… (More)

Cost-effectiveness of intensive multifactorial treatment compared with routine care for individuals with screen-detected Type 2 diabetes: analysis of the ADDITION-UK cluster-randomized controlled…

• Lin Tao, Edward C F Wilson, +8 authors Rebecca K. Simmons
• Diabetic medicine : a journal of the British…
• 2015

AIMS To examine the short- and long-term cost-effectiveness of intensive multifactorial treatment compared with routine care among people with screen-detected Type 2 diabetes. METHODS Cost-utility… (More)

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