Edward Brian Welch

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A technique for automatic retrospective correction of motion artifacts on magnetic resonance (MR) images was developed that uses only the raw (complex) data from the MR imager and requires no knowledge of patient motion during the acquisition. The algorithm was tested on coronal images of the rotator cuff in a series of 144 patients, and the improvements in(More)
Gamma-aminobutyric acid (GABA) and glutamate (Glu) levels, normalized to total creatine (tCr), were measured in the anterior cingulate and cerebellar vermis in healthy adults (n=19, age=24.6±6.4 years) using ¹H MRS at 3 T, and metabolite correlations across regions and subjects were determined. Mean anterior cingulate and cerebellar GABA/tCr ratios were(More)
A common problem in clinical MRI is anatomic misalignment of imaging slices across successive examinations. This unnecessarily complicates the radiologic assessment of anatomic change over time on serial MRI studies. To address this problem, spherical navigator echoes, which can detect rigid body motion in all six degrees of freedom, were used to guide(More)
Rigid body translations of an object in MRI create image artifacts along the phase-encode (PE) direction in standard 2DFT imaging. If two images are acquired with swapped PE direction, it is possible to determine and correct for arbitrary in-plane translational interview motions in both images directly from phase differences in the k-space acquisitions by(More)
Introduction: Magnetization transfer (MT) imaging provides contrast that is sensitive to the interactions between immobile macromolecular protons and free water protons. Clinically, this effect is most commonly characterized via the magnetization transfer ratio (MTR), a measure that has been shown to correlate with myelin content [1]. Unfortunately, MTR(More)
Interest in radial MRI (also known as projection reconstruction (PR) MRI) has increased recently for uses such as fast scanning and undersampled acquisitions. Additionally, PR acquisitions offer intrinsic advantages over standard two-dimensional Fourier transform (2DFT) imaging with respect to motion of the imaged object. It is well known that aligning each(More)
BACKGROUND The high value of the specific absorption rate (SAR) of radio-frequency (RF) energy arising from the series of RF refocusing pulses in T2-weighted (T2-w) turbo spin echo (TSE) MRI hampers its clinical application at 7.0 Tesla (7T). T2-w gradient and spin echo (GRASE) uses the speed from gradient refocusing in combination with the(More)
ACKNOWLEDGEMENTS My work could not have been achieved without assistance of a number of people from for his advice, supervision and guidance. His truly scientific attitude has made him precise and passionate in his research and has inspired and enriched my growth as a student. This work would not have been completed without your guidance and support.(More)
A common problem in clinical MRI is anatomic misalignment of imaging slices across successive examinations. This unnecessarily complicates the radiologic assessment of anatomic change over time on serial MRI studies. To address this problem , spherical navigator echoes, which can detect rigid body motion in all six degrees of freedom, were used to guide(More)