Edward A. Birge

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A mutation that causes a temperature-sensitive RecA(-) phenotype was identified in a derivative of a PolA(-) strain that failed to grow at high temperature. The mutant allele (recA200) was shown to be linked to cysC, conferred a sharply temperature-sensitive, ultraviolet-sensitive Rec(-) phenotype in the range 35 to 42 C, and in crosses failed to show(More)
In accord with the observations of other workers, unselected marker analysis of Escherichia coli K-12 transconjugants isolated from matings involving several different Hfr strains as donors has shown that most genetic exchanges and clustered either near the selected marker or near the origin of the transferred Hfr DNA. The present work increases the number(More)
One of the ribosomal proteins (30S-8B) of Escherichia coli B has a greater electrophoretic mobility than the homologous protein (30S-8K) in E. coli K. The amino acid compositions, tryptic peptides, and cyanogen bromide peptides of these two homologous proteins unambiguously indicate that the genetic locus which determines the electrophoretic mobility of(More)
The introduction of an F′ factor carrying a recB + gene into F− recB − cells which have just concluded a mating with Hfr cells results in an increased production of recombinant colony forming units involving the Hfr genes. The stimulatory effect approaches the theoretical maximum and does not occur in recB + recipients. The ability of the F− cells to be(More)