Eduardo Pareja-Tobes

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BG7 is a new system for de novo bacterial, archaeal and viral genome annotation based on a new approach specifically designed for annotating genomes sequenced with next generation sequencing technologies. The system is versatile and able to annotate genes even in the step of preliminary assembly of the genome. It is especially efficient detecting unexpected(More)
BACKGROUND Transcriptional regulation processes are the principal mechanisms of adaptation in prokaryotes. In these processes, the regulatory proteins and the regulatory DNA signals located in extragenic regions are the key elements involved. As all extragenic spaces are putative regulatory regions, ExtraTrain covers all extragenic regions of available(More)
Background. Next Generation Sequencing and other high-throughput technologies have brought a revolution to the bioinformatics landscape, by offering sheer amounts of data about previously unaccessible domains in a cheap and scalable way. However, fast, reproducible, and cost-effective data analysis at such scale remains elusive. A key need for achieving it(More)
Nowadays it is widely accepted that the bioinformatics data analysis is a r eal b ottleneck i n many r esearch act ivities r elated t o l ife s ciences. H igh-throughput t echnologies l ike N ext Generation S equencing (NGS) ha ve completely r eshaped t he bi ology a nd bi oinformatics l andscape. U ndoubtedly NGS has allowed important progress in many(More)
Today's biology involves many times the use of different omics approaches , in particular, data and information from genomes and proteins are frequently difficult to integrate. In order to manage in an integrated way the information about complete genomes and proteomes in BG7 based projects we developed the Bio4J platform ( Bio4j is a(More)
When visualizing scientific data one of the current bottlenecks is the lack of interactivity. There already exist many options to build static data visualizations such as R, Matlab or Microsoft Excel among others. On the other hand, we can also find many different pieces of software with a broader or more specific aim that however must be installed locally.(More)
As part of the Cambrian explosion of omics data, metagenomics brings to the table a specific, defining trait: its social essence. The meta prefix exerts its influence, with multitudes manifesting themselves everywhere; from samples to data analysis, from actors involved to (present and future) applications. Of these dimensions, data analysis is where needs(More)
Bio4j ( is a high-performance cloud-enabled graph-based bi oinformatics da ta pl atform. I t i s one of t he first a nd most i mportant graph databases for biological data, specially designed to cope with and manage the huge amount of data brought by NGS technologies: it i ntegrates most data available in U niProt K B (SwissProt + Trembl),(More)
Methods: MG7 i s a n ope n s ource t ool i mplemented i n J ava a nd Scala, ba sed on c loud c omputing (Amazon W eb S ervices). The g raph da ta platform B io4j ( i s us ed f or r etrieving t axonomy r elated information, w hile N ispero ( i s used f or distributing and coordinating compute tasks. Results: MG7(More)
Next Generation Sequencing (NGS) has brought a revolution to the bioinformatics l andscape, de finitely r eshaping f ields s uch a s g enomics a nd transcriptomics, by o ffering sheer amounts of data about previously inaccessible d omains i n a c heap a nd s calable w ay. Thus bi ological da ta a nalysis d e-mands, more than ever, high performance computing(More)