Eduardo M. Valcarce

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The mutagenic activity of the urine of pregnant rats treated with toxic oil syndrome-related rape seed oil or with edible oil was evaluated by means of the Ames and Green tests. It was found that the urine of the pregnant rats treated with "Jen" oil, that was related to the toxic oil syndrome, was mutagenic.
Many agents of our surroundings are mutagenic, and a significant number of the mutagenic agents are carcinogenic. It is then useful to evaluate the short-term screening test allowing to predict the carcinogenic effect of chemicals. The authors make a summary about the predictive value of the existing assays, and write about the need of the systematic use of(More)
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