Eduardo Kinoshita

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The story of Pit-1 and hypopituitarism in humans provides an excellent example of pleiotrophism or multiple phenotypic effects resulting from a single genetic alteration. It shows how defects in this single gene cause the absence o f several pituitary hormones. Three recent articles reviewed here provide examples of different mutations in this homeobox gene(More)
Functional dyspepsia is a very common gastrointestinal disorder observed in the general population, in general outpatient clinic and clinical specialty. It is associated with several treatments, hospitalization, prescription and use of several drugs. Moreover, it is related to self medication, absenteeism and also loss of productivity. The objective of this(More)
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