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Glucagon-like peptide-1 receptor (GLP-1R) agonists such as exendin-4 (Ex-4) affect eating and metabolism and are potential candidates for treating obesity and type II diabetes. In the present study, we tested whether vagal afferents mediate the eating-inhibitory and avoidance-inducing effects of Ex-4. Subdiaphragmatic vagal deafferentation (SDA) blunted the(More)
In this paper, we present a concept for an open vehicular data interface and describe it's components and architecture. We discuss the enabled applications in the context of advanced driver assistance systems with a focus on human-machine interfaces, vehicle-to-x (V2X) communication and context inference systems. We conclude by a presentation of the initial(More)
We performed studies to determine the relationship between injured vessel wall thrombogenicity, vessel wall 13-hydroxyoctadecadienoic acid (13-HODE) synthesis and cAMP levels in rabbit treated with salicylate or dipyridamole. Injured vessel wall thrombogenicity was measured as the number of 3H-adenine labelled platelets adhered to the subendothelial(More)
The number of testosterone binding sites present in rat uterine cytosol varied regularly during the estrous cycle, reaching a trough at metestrus and a peak at proestrus. Treating ovariectomized and adrenalectomized rats for 2 days with estradiol resulted in a 3-4-fold increase in the number of binding sites per uterus. Estradiol withdrawal induced a(More)
To test the possibility that different doses of heparin or other sulfated polysaccharides are required to inhibit thrombosis initiated by different stimuli, we compared the effects of heparin (HEP), pentosan polysulfate (SP54) and dermatan sulfate (DS) on the inhibition of thrombus formation induced by either I) tissue thromboplastin; II) thrombin; or III)(More)
Following brief summaries of the overlapping lives of Herbart, E. H. Weber, Fechner, and Helmholtz, it is shown that Herbart and Fechner agreed about the nature of mental science in three particular ways. First, both adopted ideas about force and energy from the physical sciences; Herbart's interplay of Vorstellungen assumed that equilibrium states were(More)
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