Eduard Friedrich Stange

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The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis Gert Van Assche⁎, Axel Dignass⁎, Julian Panes, Laurent Beaugerie, John Karagiannis, Mathieu Allez, Thomas Ochsenkühn, Tim Orchard, Gerhard Rogler, Edouard Louis, Limas Kupcinskas, Gerassimos Mantzaris, Simon Travis, Eduard Stange for(More)
The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations Gert Van Assche ⁎, Axel Dignass ⁎, Walter Reinisch, C. Janneke van der Woude, Andreas Sturm, Martine De Vos, Mario Guslandi, Bas Oldenburg, Iris Dotan, Philippe Marteau, Alessandro Ardizzone, Daniel C. Baumgart, Geert D'Haens, Paolo(More)
Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management Axel Dignass ⁎, James O. Lindsay, Andreas Sturm, Alastair Windsor , Jean-Frederic Colombel , Mathieu Allez , Gert D'Haens, André D'Hoore, Gerassimos Mantzaris , Gottfried Novacek , Tom Öresland, Walter Reinisch, Miquel Sans, Eduard(More)
5. Medical management of active ulcerative colitis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 5.1. General . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 5.1.1. Disease activity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .(More)
Recent evidence suggests that probiotic bacteria may stabilize gut barrier function via induction of anti-microbial peptides such as defensins. This study aimed to elucidate the induction mechanism of the human beta defensin-2 (hBD-2) gene by different probiotic lactobacillus strains. The expression of hBD-2 mRNA peaked at 6 h of incubation upon treatment(More)
Little is known about the defensive mechanisms induced in epithelial cells by pathogenic versus probiotic bacteria. The aim of our study was to compare probiotic bacterial strains such as Escherichia coli Nissle 1917 with nonprobiotic, pathogenic and nonpathogenic bacteria with respect to innate defense mechanisms in the intestinal mucosal cell. Here we(More)
Defensins are endogenous antimicrobial peptides that protect the intestinal mucosa against bacterial invasion. It has been suggested that deficient defensin expression may underlie the chronic inflammation of Crohn disease (CD). The DNA copy number of the beta-defensin gene cluster on chromosome 8p23.1 is highly polymorphic within the healthy population,(More)
J.F. Rahier ⁎, S. Ben-Horin, Y. Chowers, C. Conlon, P. De Munter, G. D'Haens, E. Domènech, R. Eliakim, A. Eser, J. Frater, M. Gassull, M. Giladi, A. Kaser, M. Lémann, T. Moreels, A. Moschen, R. Pollok, W. Reinisch, M. Schunter, E.F. Stange, H. Tilg, G. Van Assche, N. Viget, B. Vucelic, A. Walsh, G. Weiss, Y. Yazdanpanah, Y. Zabana, S.P.L. Travis, J.F.(More)