Edoardo Sicurezza

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OBJECTIVE The purpose of this study was to assess the influence of rapid maxillary expansion (RME) on orbital volume and aperture width measurements by using freeware software with DICOM data from low-dose-protocol multidetector computerized tomography (MDCT). STUDY DESIGN The subjects consisted of 30 patients (12 male, 18 females) treated with a Hyrax(More)
This study investigated if tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) immunohistochemical expression in human temporomandibular joint (TMJ)-degenerated disks correlates to the degree of tissue damage to elucidate the possible involvement of this apoptotic pathway in TMJ disk degeneration. Twenty-one TMJ displaced disk from 12 patients(More)
AIMS To evaluate, immunohistochemically, the presence and distribution of lubricin in human temporomandibular joint (TMJ) discs without any degenerative changes, obtained from autopsies, in order to elucidate the TMJ lubrication system and disc tribology. METHODS Immunohistochemistry for lubricin detection was carried out on 34 TMJ discs. Any disc had(More)
OBJECTIVE To test the null hypothesis that circumaxillary sutures do not show bony displacement in response to rapid maxillary expansion (RME) therapy. MATERIALS AND METHODS Subjects consisted of eight growing patients (two male and six female) with Angle Class I malocclusion, bilateral posterior crossbite, transverse maxillary deficiency, deep palatal(More)
BACKGROUND TRAIL is a transmembrane protein that induces apoptosis in various tissues including alveolar bone. Its in vitro expression can be activated by several methods, such as RANKL administration and cell scraping. Expression of TRAIL and its receptors DR5 and DcR2 was examined in osteoclast-like cells to analyze their effects on cell lifespan and to(More)
OBJECTIVES β-defensin-4 is a member of antimicrobial peptides (APs) of the immunity system. This molecule has antimicrobial activity but it seems to be involved in articular inflammatory processes too, as it happens during osteoarthritic disease (OA). Considering the possible relation existing between (OA) and temporomandibular disorders (TMD), the aim of(More)
OBJECTIVES The aim of this study was to examine accuracy in landmark identification on digital postero-anterior cephalograms, (PAC) assessing the intra-observer and the inter-observer repeatability in determining these landmarks. MATERIALS AND METHODS Twenty postero-anterior digital cephalometric radiographs were randomly selected from data files of(More)
OBJECTIVE To investigate condylar symmetry and condyle fossa relationships in subjects with functional posterior crossbite comparing findings before and after rapid maxillary expansion (RME) treatment through low-dose computed tomography (CT). MATERIALS AND METHODS Twenty-six patients (14 girls and 12 boys, mean age 9.6 ± 1.4 years) with functional(More)
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