Edoardo De Benedetti

Learn More
BACKGROUND Intimal hyperplasia is the principal mechanism of in-stent restenosis. Matrix metalloproteinases (MMPs) play a key role in intimal growth after balloon angioplasty (BA). Little is known, however, about MMP expression after stent implantation (ST). We investigated whether MMP9 and MMP2 are differentially expressed after ST and BA. METHODS AND(More)
A new method for spike sorting of tetrode recordings during data acquisition is introduced. For each tetrode channel, putative spikes are detected by means of a threshold, and then convolved with a cascade of wavelet filters. These transformed putative spikes are averaged and this average is used as a matched filter to find portions of signals that are(More)
S ince they were first introduced 17 years ago, 1 bare metallic stents have improved the outcome of angio-plasty. 2 However, in-stent restenosis (ISR) remains a major limitation with an incidence of additional revas-cularisation of 17–21 %. Among the several approaches proposed to address this problem, vascular brachytherapy (VBT) has given the best(More)
  • 1