Edith H. Weinberg

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1. Dogs were treated with growth hormone for three months under controlled conditions, dietary calcium absorption efficiency was measured by administration of47Ca and45Ca, and calcium pool size, pool turnover, bone mineral accretion, and endogenous fecal calcium excretion were measured using the I.V.45Ca tracer. Identical studies were performed in each(More)
Five mature dogs were studied five to eight months after insertion of a newly designed acetabular component that eliminates the use of bone cement in total hip arthroplasty (THA). The component was hemispheric, with a layer of porous metal on its outside surface. It initially was fixed to the innominate bone by screws passed through projections from the(More)
A new method is presented by which an increase in cortical bone mass over time can be determined from morphometric analysis of sections of undemineralized bone under the optical microscope. The method depends on the long-duration, continuous labeling of new bone by tetracycline during the experimental period. In addition, a comparison of the rates of new(More)
Studies of flexible plates made of plastic have shown that less osteoporosis develops beneath them than beneath rigid metal plates. However, to date plastic plates of appropriate physical properties and biocompatibility are not available for use in humans. To determine if a similar beneficial effect could be obtained using metal plates, the effects of thick(More)
The effect of phosphate supplementation on bone remodeling was assessed in six mature, healthy beagle dogs. The phosphate supplement was given in divided doses orally, daily for 12 weeks in the form of a neutral potassium phosphate preparation. The dose averaged 108 mg P/kg per day, which is double the normal canine phosphorus intake. Bone remodeling was(More)
In intact adult dogs of both sexes exogenous growth hormone induced a marked increase in new bone formation. The net effect on resorption could not be defined quantitatively but endosteal resorption was decreased. Intracortical resorption was increased but intracortical porosity rose only slightly. In addition to the decrease in endosteal resorption, there(More)