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Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs

• Bálint Csörgő, Tamás Fehér, Edit Tímár, Frederick R. Blattner, György Pósfai
• Microbial cell factories
• 2012

BACKGROUND Molecular mechanisms generating genetic variation provide the basis for evolution and long-term survival of a population in a changing environment. In stable, laboratory conditions, the… (More)

Complementation between inactive fragments of SssI DNA methyltransferase

• Krystyna Ślaska-Kiss, Edit Tímár, Antal Kiss
• BMC Molecular Biology
• 2012

Silencing mammalian genes by targeted DNA (cytosine-5) methylation of selected CG sites in the genome would be a powerful technique to analyze epigenomic information and to study the roles of DNA… (More)

Simplified identification of aerobic spore-formers in the investigation of foods.

• Tamás Deák, Edit Tímár
• International journal of food microbiology
• 1988

Bacillus spp. are among the main spoilage organisms in food due to their versatile metabolism and heat-resistant spores. Except for B. cereus, no specific identification method is available, although… (More)

Pathomechanism and clinical signs of mould sensitization in the asthmoid bronchitis syndrome of young children.

• Peter Osvath, G Tóth, +5 authors László Endre
• Acta allergologica
• 1974

Changing the recognition specificity of a DNA-methyltransferase by in vitro evolution.

• Edit Tímár, Gergely Groma, Antal Kiss, P. Venetianer
• Nucleic acids research
• 2004

The gene coding for the SinI DNA-methyltransferase, a modification enzyme able to recognize and methylate the internal cytosine of the GG(A)/(T)CC sequence, was subjected to in vitro mutagenesis,… (More)

In vivo DNA protection by relaxed-specificity SinI DNA methyltransferase variants.

• Edit Tímár, P. Venetianer, Antal Kiss
• Journal of bacteriology
• 2008

The SinI DNA methyltransferase, a component of the SinI restriction-modification system, recognizes the sequence GG(A/T)CC and methylates the inner cytosine to produce 5-methylcytosine. Previously… (More)

Genome-Wide Abolishment of Mobile Genetic Elements Using Genome Shuffling and CRISPR/Cas-Assisted MAGE Allows the Efficient Stabilization of a Bacterial Chassis.

• Kinga Umenhoffer, Gábor Draskovits, +9 authors György Pósfai
• ACS synthetic biology
• 2017

The ideal bacterial chassis provides a simplified, stable and predictable host environment for synthetic biological circuits. Mutability and evolution can, however, compromise stability, leading to… (More)

HM-PAO-labeled leukocyte scintigraphy in pediatric patients with inflammatory bowel disease.

• Miklós Papós, Andrea Várkonyi, +5 authors L. Csernay
• Journal of pediatric gastroenterology and…
• 1996

Leukocyte scintigraphy (LS) was performed in 20 pediatric patients with inflammatory bowel disease (IBD: 10 with ulcerative colitis, 2 with indeterminate colitis, and 8 with Crohn disease) in… (More)

Coeliac disease: always something to discover.

• Andrea Várkonyi, Martin Boďa, Emöke Endreffy, István Balázs Németh, Edit Tímár
• Scandinavian journal of gastroenterology…
• 1998

The authors present more than 20 years' experience with coeliac disease, with a summary of their published studies. Hair shaft characteristics were determined by scanning electron microscopy. Hair… (More)

Construction and study of altered specificity DNA methyltransferases Ph. D. thesis summary

• Edit Tímár
• 2016

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