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beta(2) integrins and Fcgamma receptors are critically involved in neutrophil activation at the site of inflammation. Both receptor types trigger a receptor-proximal tyrosine phosphorylation cascade through Src family kinases and Syk, but further downstream signaling events are poorly understood. We show that phospholipase C (PLC) gamma2 is phosphorylated(More)
Insects often used as accumulation indicators of hazardous elements. Pitfall traps with ethylene glycol as trapping fluid are frequently used to collect insects. We studied the effect of glycol and preservation with ethanol on the elemental composition of hand collected firebugs. Control samples were stored in a freezer and the following treatments were(More)
BACKGROUND Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase-producing pathogens, such as Streptococcus pneumoniae. Increasing data support a pathogenic role of neuraminidase in the development of S. pneumoniae-associated haemolytic uraemic(More)
Amphibians, particularly frogs and toads, are increasingly used as bioindicators of contaminant accumulation in pollution studies. We developed an analytical technique to analyse their elemental contents based on a small amount of toe bone samples. This method is environment-friendly as, unlike traditional methods, it is not necessary to kill animals during(More)
OBJECTIVE The Syk tyrosine kinase plays an important role in diverse functions in hematopoietic lineage cells. Although previous in vitro and pharmacologic analyses suggested Syk to be a possible player in the development of autoimmune arthritis, no in vivo genetic studies addressing that issue have yet been reported. The aim of the present study was to(More)
Seasonal changes in water relations, production and mineral composition were studied in a sward ofCynodon dactylon (L). Pers. subjected to water deficits during a dry summer, and at recovery in autumn. The experiment was carried out under Mediterranean field conditions. Water deficits during summer reduced total dry matter production by 60%, but in autumn(More)
Foliage dust contains heavy metal that may have harmful effects on human health. The elemental contents of tree leaves and foliage dust are especially useful to assess air environmental pollution. We studied the elemental concentrations in foliage dust and leaves of Acer pseudoplatanus along an urbanization gradient in Vienna, Austria. Samples were(More)
Although Src family kinases participate in leukocyte function in vitro, such as integrin signal transduction, their role in inflammation in vivo is poorly understood. We show that Src family kinases play a critical role in myeloid cell-mediated in vivo inflammatory reactions. Mice lacking the Src family kinases Hck, Fgr, and Lyn in the hematopoietic(More)
Urban soil is an important component of urban ecosystems. This study focuses on heavy metal contamination in soils of Wien (Austria) and results are compared to those for a few large European cities. We analysed the elemental contents of 96 samples of topsoil from urban, suburban and rural areas in Wien along a dynamic (floodplain forest) and a stable(More)
Environmental health is an essential component of the quality of life in modern societies. Monitoring of environmental quality and the assessment of environmental risks are often species based on the elemental concentration of deposited dust. Our result suggested that stomata size and distribution were the most important factors influencing the accumulation(More)