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Genetically modified mice represent useful tools for traumatic brain injury (TBI) research and attractive preclinical models for the development of novel therapeutics. Experimental methods that minimize the number of mice needed may increase the pace of discovery. With this in mind, we developed and characterized a prototype electromagnetic (EM) controlled(More)
Apolipoprotein E4 (APOE4) genotype is a risk factor for poor outcome after traumatic brain injury (TBI), particularly in young patients, but the underlying mechanisms are not known. By analogy to effects of APOE4 on the risk of Alzheimer disease (AD), the APOE genotype may influence β-amyloid (Aβ) and tau deposition after TBI. To test this hypothesis, we(More)
  • Essa L Gross, John Gierke, Wayne Pennington, Luis Meza, Denia Acuña, Evelio Lopez +10 others
  • 2015
Manual pumping test method for characterizing the productivity of drilled wells equipped with rope pumps", Master's Thesis, I would like to thank Antoinette Kome for her guidance and support of the work, as well as her assistance in facilitating information exchanges with the various Nicaraguan ministries and institutions essential for the completion of(More)
  • Essa L Gross, John Gierke, Wayne Pennington, Luis Meza, Denia Acuña, Evelio Lopez +10 others
  • 2008
I would like to thank Antoinette Kome for her guidance and support of the work, as well as her assistance in facilitating information exchanges with the various Nicaraguan ministries and institutions essential for the completion of this study. My gratitude also extends to the Dolores-Aragon, Miranda, Vargas, and Espinoza families of Santa Rita, Nicaragua(More)
Leibniz and Newton, both independently credited as inventors of calculus , relied on the concept of an infinitesimal (nonzero " numbers " that were " infinitely small ") in their development. Our standard rigorous treatment of calculus involves an " arbitrary epsilon " limit definiton. There's an alternative rigorous study of calculus beyond the limits of(More)
Preface Our capabilities of both generating and collecting data have been increasing rapidly in the last several decades. Contributing factors include the widespread use of bar codes for most commercial products, the computerization of many business, scientiic and government transactions and managements, and advances in data collection tools ranging from(More)
Our capabilities of both generating and collecting data have been increasing rapidly in the last several decades. Contributing factors include the widespread use of bar codes for most commercial products, the computerization of many business, scientiic and government transactions and managements, and advances in data collection tools ranging from scanned(More)
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