Learn More
Micro- and nanoscale engineering approaches in medicine have the potential to recreate physiologically relevant stem cell microenvironments to enhance our understanding of stem cell behaviour and bring stem cell therapy closer to fruition. The realization of such advancements will impact a number of therapeutic applications, the most immediate of which may(More)
This paper describes a new technique to measure urine volume in patients with urinary bladder dysfunction. Polypyrrole - an electronically conducting polymer - is chemically deposited on a highly elastic fabric. This fabric, when placed around a phantom bladder, produced a reproducible change in electrical resistance on stretching. The resistance response(More)
This article presents an image processing approach dedicated for a blind mobility aid facilitated through visual intracortical electrical stimulation. The method examines a display framework based on the distances related to a scene. The distances of objects to the walker are measured using a size perspective method which uses only one camera without any(More)
A hybrid microfluidic/IC capacitive sensor is presented in this paper for highly integrated lab-on-chips (LoCs). We put forward the design and implementation of a charge based capacitive sensor array in 0.18-mum CMOS process. This sensor chip is incorporated with a microfluidic channel using direct-write microfluidic fabrication process (DWFP). The design,(More)
An improved-accuracy algorithm for real-time nanopore-based signal detection (e.g. base calling) is introduced. The approach is based on the cumulative sum technique but employs a decision-directed policy coupled with a post-decision correction mechanism. These additions allow the improved detector to achieve at least a 10× accuracy improvement over(More)
In this paper, we present a bacteria growth monitoring technique using a complementary metal-oxide semiconductor capacitive sensor. The proposed platform features a differential capacitive readout architecture with two interdigitized reference and sensing electrodes. These electrodes are exposed to pure Luria-Bertani (LB) medium and Escherichia Coli (E.(More)
We put forward an impedometric protein-based biosensor platform suitable for point-of-care diagnostics. A hand-held scale impedance reader system is described for the detection of corresponding physiochemical changes as the immobilized proteins bind to the analyte molecules in the proximity of the microfabricated electrodes. Specifically, we study the(More)
Recent advances in integrated biosensors, wireless communication and power harvesting techniques are enticing researchers into spawning a new breed of point-of-care (POC) diagnostic devices that have attracted significant interest from industry. Among these, it is the ones equipped with wireless capabilities that drew our attention in this review paper.(More)
In this paper, we present a hybrid capacitive sensor featuring a 0.18mum CMOS integrated circuit incorporated with a microfluidic channel and a polyelectrolyte sensing layer (PSL). We describe the formation of ultrathin PSL atop a microfabricated gold electrode (MGE) and CMOS sensor, and thereafter demonstrate the viability of this new approach for Lab-(More)