Data based on independent interviews with 45 herbalists of the Luo of Siaya District, Kenya, comprised 1129 remedy reports and related to 330 species of plants. While 49% of the remedies were… (More)
Activity in an in vitro assay with Giardia lamblia provided a test of the validity of a quantitative methodology used in an ethnobotanical survey of the Luo people of the Lake Victoria basin of Kenya… (More)
The new FDA Guidance for Industry BA and BE Studies for Orally Administered Drug Products--General Considerations and Average, Population, and Individual Approaches to Establishing Bioequivalence… (More)
Two moment-based scaled definitions of individual bioequivalence are discussed. Based on a mixed effects linear model, their evaluations respectively lead to an unweighted (theta(11)) and a… (More)
The evaluation of individual bioequivalence (IBE) by bootstrap resampling using common statistical software, for example SAS, is extremely time consuming. In this article, an estimation procedure… (More)
Different mixed-effects models were compared to evaluate the population dose–response and relative potency of two albuterol inhalers. Bronchodilator response was measured after ascending doses of… (More)
Confidence intervals of proposed individual bioequivalence metrics are difficult to determine in closed form because their stochastic distributions are unknown. In this article, it is shown that,… (More)
OBJECTIVE
To call for harmonisation of good clinical practice guidelines in East Africa as one of the necessary precedents to enhancing their quality and quantity in the region.
DATA SOURCES
There… (More)