Eberhard Horn

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1. In walking flies,Calliphora erythrocephala, gravity specific stimulation of proprioceptors of the legs causes positional reflexes of the head. For rotations around the longitudinal axis this response is maximal if the transverse axis of the fly is tilted 90° relative to the horizontal. For rotations around the transverse axis the head of the fly(More)
Since last century, the functions of the vestibular organ have been well investigated in vertebrates. One of the main problems is the analysis of compensation for rotatory movements and asymmetrical posture of limbs and eyes after unilateral labyrinthectomy [1]. Much work has been done in adult animals, but only a few investigations are available that take(More)
In toads,Bufo bufo L., ACTH (1 I.U.) causes a retardation of extinction compared with Ringer administration irrespective of whether the animals have received the ACTH injection before or at the end of acquisition. Treatment with ACTH 20 min prior to acquisition lowers the starting activity. Therefore, habituation is completed earlier than in Ringer(More)
The effects of altered gravitational forces (AGF) on the development of the static vestibulo-ocular reflex (VOR) were investigated in Xenopus laevis tadpoles exposed to hypergravity (1.4g; 3g) or microgravity conditions (German spacelab mission D-2) for 9–10 days. The effects of light conditions during development were also tested by exposing tadpoles to(More)
In the Southern Clawed Toad,Xenopus laevis, the compensation of vestibular induced behavioural deficits were investigated in relation to development. In hemilabyrinthectomized tadpoles and juveniles, the time of compensation for movement and eye posture defects depends on the time of operation. As a rule, the older the animals are at the time of operation(More)
When a walking fly approaches a stationary object two types of body movements are distinguishable. Type I body movements are characterized by low frequencies (0.4–1.3 Hz) and large amplitudes (28–65°). Superimposed on these movements are type II body movements which are characterized by high frequencies (7.3–10.6 Hz) and small amplitudes (5.9–8.2°) (Figs.(More)
1. In all hemimetabolic neopterous insects tested and also in Megaloptera, Mecoptera and Coleoptera the directional sensitivity to gravity is mainly or exclusively mediated by the body weight pressing on the legs. 2. In Enallagma cyathigerum (Odonata), Chrysopa vulgaris (Planipennia), Pieris napi (Lepidoptera) and all the Hymenoptera tested the pressure of(More)
The antibody trastuzumab (Herceptin) has substantially improved overall survival for patients with aggressive HER2-positive breast cancer. However, about 70% of all treated patients will experience relapse or disease progression. This may be related to an insufficient targeting of the CD44(high)CD24(low) breast cancer stem cell subset, which is not only(More)
Tumorbiology of ovarian cancer remains unclear. However, it is known that ovarian tumors, especially carcinomas, show elevated expression of glucose membrane transporters for facilitated glucose uptake. It can be assumed that increased glucose uptake leads to higher glucose metabolism. The energy resources of fully malignant transformed carcinomas are(More)
In freely walking flies,Drosophila melanogaster, stationary stripes induce fixation processes. If two vertical black stripes (width 6°) are presented against an illuminated white background and if the two stripes are separated by an angular distance ofα ν < 60°, the flies prefer the direction of the bisector of the angle between the two objects, i.e. the(More)