Earnest Foster

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The localization of TrkB, a signal transducing receptor for brain-derived neurotrophic factor and neurotrophin-4, was studied in the rat mandibular molar pulp during development and following nerve injury. Sections were incubated with rabbit polyclonal antiserum against the catalytic part of the TrkB receptor, thus only binding to full-length TrkB(More)
In this paper, a generic optimization problem arising in supply chain design is modeled in a game theoretic framework and solved as a decentralized problem using a mechanism design approach. We show that the entities in a supply chain network can be naturally modeled as selfish, rational, and intelligent agents interested in maximizing certain payoffs. This(More)
The expression of full-length trkB protein, the functional high affinity receptor for BDNF and NT-4, was examined by immunohistochemistry in adult rat L4-L5 dorsal root ganglia after different types of sciatic nerve lesions. In normal ganglia, 52.5% of the neurons showed trkB-like immunoreactivity. Size measurements demonstrated that trkB-like(More)
General Motors (GM) has developed a first proof-of-concept simulation model to explore impacts of various fire events in automotive paint shop operations. The approach uses a chronological event tree structure to assess effectiveness of various fire protection options to reduce the potential for significant property damage and loss of production capability.(More)
This paper presents problems encountered within the simulation modeling community of General Motors when they are faced with the requirement to verify all new plant designs for their entire global manufacturing enterprise. Given that the Body Shop, Paint Shop, and General Assembly areas of an automotive plant are modeled independently in two different(More)
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