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This paper presents 3DCoffee@igs, a web-based tool dedicated to the computation of high-quality multiple sequence alignments (MSAs). 3D-Coffee makes it possible to mix protein sequences and structures in order to increase the accuracy of the alignments. Structures can be either provided as PDB identifiers or directly uploaded into the server. Given a set of(More)
This paper presents Tcoffee@igs, a new server provided to the community by Hewlet Packard computers and the Centre National de la Recherche Scientifique. This server is a web-based tool dedicated to the computation, the evaluation and the combination of multiple sequence alignments. It uses the latest version of the T-Coffee package. Given a set of(More)
When comparing OpenMP to other parallel programming models, it is easier to choose between OpenMP and MPI than between OpenMP and POSIX Threads (Pthreads). With languages like C and C++, developers frequently have chosen Pthreads to incorporate parallelism in applications. Few developers are currently using OpenMP C/C++, but they should. We show that(More)
Developing testbenches for dynamic functional verification of hardware designs is a software-intensive process that lies on the critical path of electronic system design. The increasing capabilities of electronic components is contributing to the construction of complex verification environments that are increasingly difficult to understand, maintain,(More)
The daily peaks and valleys in energy demand create inefficiencies and expense in the operation of the electricity grid. Valley periods force utilities to curtail renewable energy sources such as wind as their unpredictable nature makes it difficult to maintain line frequency across the network within target bounds. Peak periods require additional(More)
Socio-technical MAS are an intrinsic part of our daily lives. Domains like energy, transport, etc. are increasingly using technology to allow individual users to adapt to, and even influence the aggregate performance of the system. This raises expectations of fairness and equitability, while being engaged in such MAS. Given the autonomous and decentralized(More)
This article describes Decentralised Emergence Detection (DETect), a novel distributed algorithm that enables agents to collaboratively detect emergent events in Complex Adaptive Systems (CAS). Non-deterministic interactions between agents in CAS can give rise to emergent behaviour or properties at the system level. The nature, timing, and consequence of(More)
The complex pathophysiology of chronic ulceration in diabetic patients is poorly understood; diabetes-related lower limb amputation is a major health issue, which has limited effective treatment regimes in the clinic. This study attempted to understand the complex pathology of hyperglycemic wound healing by showing profound changes in gene expression(More)
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