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Rhodopsin density and absolute threshold were determined in 11 patients with retinitis pigmentosa (RP) and nine normal subjects. In eight patients with familial histories suggesting recessive inheritance, the retinal areas studied showed marked decrease in sensitivity which was related to rhodopsin loss, probably via a log-linear relationship. The other(More)
Intense red light adaptation of one eye lowers the dark adapted ("absolute") threshold of a 661 nm, extrafoveal, 1.02 deg test flash in the other eye, by about 0.15 log units, for 10-15 min. This effect ("interocular sensitization") also occurs with an extrafoveal 491 nm test, but does not occur if the 661 nm test is foveal, or is made small and brief. Blue(More)
Extrafoveal thresholds for 660 nm test flashes were measured for the two eyes separately following 30 min of dark adaptation. Then, the right eye was exposed to red light while the left eye was covered. Thresholds in the adapted right eye recovered to a plateau raised about 0.3 log units above the level measured in the dark. In contrast, thresholds in the(More)
We have examined the electroretinographic responses, the psychophysically determined course of dark adaptation and/or the scotopic and photopic (static) perimetric profile of the uninjured eyes of 11 patients with unilateral intraocular foreign bodies. Most of the patients showed subnormal ERG amplitudes over a range of light intensities, and subnormal(More)