Molecules as documents of evolutionary history.
- E. Zuckerkandl, L. Pauling
- BiologyJournal of Theoretical Biology
- 1 March 1965
Standardized nomenclature for Alu repeats
- M. Batzer, P. Deininger, E. Zuckerkandl
- BiologyJournal of Molecular Evolution
- 2004
This paper presents a probabilistic analysis of the H2O2 gene that was constructed at the Lawrence Livermore National Laboratory during the 1990s as well as a comparison study conducted at the University of California at Davis in 2011.
Cytosine deamination plays a primary role in the evolution of mammalian isochores.
- K. J. Fryxell, E. Zuckerkandl
- BiologyMolecular biology and evolution
- 1 September 2000
Analysis of human DNA sequence data confirms that this is the case for 5-methylcytosine and that cytosine deamination causes the majority of all C-->T and G-->A transitions in mammals, and that DNA base composition each affect the other, forming a positive feedback loop that facilitates divergent genetic drift.
Chemical Paleogenetics. Molecular "Restoration Studies" of Extinct Forms of Life.
- L. Pauling, E. Zuckerkandl, T. Henriksen, Rolf Lövstad
- Chemistry
- 1963
Revisiting junk DNA
- E. Zuckerkandl
- BiologyJournal of Molecular Evolution
- 1 March 1992
It is pointed out that the inverse correlation between functional constraints and rates of substitution cannot be claimed to be a pillar of the neutral theory, because it is also predicted from a selectionist view-point.
“Homology” in proteins and nucleic acids: A terminology muddle and a way out of it
- G. Reeck, C. D. Haën, E. Zuckerkandl
- BiologyCell
- 28 August 1987
Evolutionary processes and evolutionary noise at the molecular level
- E. Zuckerkandl
- BiologyJournal of Molecular Evolution
- 1 September 1976
It is predicted that proteins that do not possess general- function sites besides their specific-function sites tend to −freeze− their primary structure, which limits the use of weighted functional density as an indicator of the overall degree of interaction specificity of a protein to values that are not close to unity.
Combinatorial epigenetics, "junk DNA", and the evolution of complex organisms.
- E. Zuckerkandl, Giacomo Cavalli
- BiologyGene
- 1 April 2007
Neutral and Nonneutral Mutations: The Creative Mix—Evolution of Complexity in Gene Interaction Systems
- E. Zuckerkandl
- BiologyJournal of Molecular Evolution
- 1997
Nearly neutral mutations may, at times, constitute a required pathway for increases in gene interaction complexity, and the process seems to point to an inbuilt drive-built into the gene interaction system itself-toward the evolution of higher organisms.
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