E. Wijdicks

Publications1,279
h-index88
Citations31,681
Highly Influential Citations1,041
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Guidelines for the Early Management of Adults With Ischemic Stroke
Purpose— Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and ot...
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Validation of a new coma scale: The FOUR score
TLDR
A new coma score, the FOUR (Full Outline of UnResponsiveness) score, which provides greater neurological detail than the GCS, recognizes a locked‐in syndrome, and is superior to the G CS due to the availability of brainstem reflexes, breathing patterns, and the ability to recognize different stages of herniation.
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Definition of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies: Proposal of a Multidisciplinary Research Group
TLDR
An international ad hoc panel of experts involved in subarachnoid hemorrhage research developed and proposed a definition of DCI to be used as an outcome measure in clinical trials and observational studies, which reflect the most relevant morphological and clinical features ofDCI.
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Community-acquired bacterial meningitis in adults.
TLDR
This review summarizes recent changes in the treatment of adults with community-acquired bacterial meningitis and details the approach to complications such as transtentorial herniation, hydrocephalus, and focal seizures.
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Evidence-based guideline update: Determining brain death in adults
TLDR
There is insufficient evidence to determine the minimally acceptable observation period to ensure that neurologic functions have ceased irreversibly and if newer ancillary tests accurately confirm the cessation of function of the entire brain.
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Determining brain death in adults
TLDR
This document outlines diagnostic criteria for the chical diagnosis of brain death in patients older than 18 years and the sensitivity and specificity of laboratory tests that confirm the clinical diagnosis ofbrain death are discussed.
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Predictors of neurologic outcome in hypothermia after cardiac arrest
TLDR
To evaluate the predictive value of neurologic prognostic indicators for patients treated with hypothermia after surviving cardiopulmonary arrest, a large number of indicators were found to be positive.
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Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinion.
TLDR
All experts agreed that anticoagulation should be urgently reversed, but how to achieve it varied from use of prothrombin complex concentrates only to recombinant factor VIIa only, and all experts favored resumption of warfarin therapy within 3 to 10 days of ICH in stable patients in whom subsequent antICOagulation is mandatory.
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Prognostic value of myoclonus status in comatose survivors of cardiac arrest
TLDR
It is concluded that myoclonus status in postanoxic coma should be considered an agonal phenomenon that indicates devastating neocortical damage and its presence in comatose patients after cardiac arrest must strongly influence the decision to withdraw life support.
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Hyponatremia in Critically Ill Neurological Patients
TLDR
Hyponatremia may complicate the clinical course of many acute neurologic and neurosurgical disorders and Physicians working with critically ill neurologic patients should be familiar with management strategies addressing these underlying pathophysiological mechanisms.
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