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CC chemokine receptor gene polymorphisms in Czech patients with pulmonary sarcoidosis.
Genes for the chemokine receptors CCR5 and CCR2 are characterized by polymorphisms resulting in a nonfunctional receptor expression. Ligands for CCR2 and CCR5 (chemokines monocyte chemotacticExpand
Biological aspects of Lyme disease spirochetes: unique bacteria of the Borrelia burgdorferi species group.
BACKGROUND Borrelia burgdorferi sensu lato is a group of at least twelve closely related species some of which are responsible for Lyme disease, the most frequent zoonosis in Europe and the USA. ManyExpand
DNA vaccines: are they still just a powerful tool for the future?
Vaccination is historically one of the most successful strategies for the prevention of infectious diseases. For safety reasons, modern vaccinology tends toward the usage of inactivated or attenuatedExpand
Endotoxin-minimized HIV-1 p24 fused to murine hsp70 activates dendritic cells, facilitates endocytosis and p24-specific Th1 response in mice.
Heat shock proteins hsp70 and gp96 have been confirmed as adjuvants enabling induction of cell- and antibody-mediated immunity specific to associated protein or peptide antigens due to the activationExpand
Prevention of Lyme Disease: Promising Research or Sisyphean Task?
Borrelia burgdorferi sensu lato (Spirochaetes) is a group of at least 12 closely related species, some of which are responsible for chronic zoonotic infection that may cause Lyme disease. The onlyExpand
Allergen standardization.
The article summarises current knowledge about the preparation and standardisation of treatment and diagnosis of allergies. It summarises the basic conceptions, units, methods and conditions forExpand
The source and role of RANTES in interstitial lung disease.
The chemokine "regulated on activation, normal T-cell expressed and secreted" (RANTES) is a potent eosinophil and lymphocyte attractant with particular preference for CD45RO+ T-cells and eosinophils.Expand
Differentiation of Trichophyton mentagrophytes Arthrospores Controlled by Physical Factors
Summary: Differentiation of arthrospores in one strain of Trichophyton mentagrophytes is induced on agar medium and human hair by increased tension of carbon dioxide (8%) in the atmosphere. TheseExpand
Isolation and characterization of an immunogenic fragment of heat shock protein 60 from Trichophyton mentagrophytes
Heat shock protein 60 (hsp60) were isolated from several fungal, protozoal and many bacterial pathogens and successfully used for protective vaccination in some infection models. This work focuses onExpand
Heat shock proteins in autoimmune diseases.
  • M. Raška, E. Weigl
  • Biology, Medicine
  • Biomedical papers of the Medical Faculty of the…
  • 1 December 2005
Heat shock proteins (hsp's) are among the most conserved proteins in evolution. They have been identified as important pathogen-related antigens as well as autoantigens suitable for construction ofExpand