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Antibiotic resistance-the need for global solutions.
The causes of antibiotic resistance are complex and include human behaviour at many levels of society; the consequences affect everybody in the world. Similarities with climate change are evident.Expand
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mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients
Background:In an effort to raise protective antiviral immunity, dendritic cell immunotherapy was evaluated in six adults infected with human immunodeficiency virus (HIV)-1 and stable under highlyExpand
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Transcriptome analysis of monocyte-HIV interactions
BackgroundDuring HIV infection and/or antiretroviral therapy (ART), monocytes and macrophages exhibit a wide range of dysfunctions which contribute significantly to HIV pathogenesis andExpand
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Antibiotic stewardship in low- and middle-income countries: the same but different?
BACKGROUND Antibiotic resistance (ABR) is a quickly worsening problem worldwide, also in low- and middle-income countries (LMICs). Appropriate antibiotic use in humans and animals, i.e. antibioticExpand
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A retrospective observational study on the efficacy of colistin by inhalation as compared to parenteral administration for the treatment of nosocomial pneumonia associated with multidrug-resistant
BackgroundColistin is used as last treatment option for pneumonia associated with multidrug-resistant (MDR) Pseudomonas spp.. Literature about the best administration mode (inhalation versusExpand
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Clinical Utility of the Nonstructural 1 Antigen Rapid Diagnostic Test in the Management of Dengue in Returning Travelers With Fever
Abstract Background Rapid diagnostic test (RDT) detecting the nonstructural 1 (NS1) antigen is increasingly used for dengue diagnosis in endemic and nonendemic settings, but its clinical utility hasExpand
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Clinical bacteriology in low-resource settings: today's solutions.
TLDR
We explore what constitutes successful implementation of clinical bacteriology in low-resource settings and describe a framework for implementation that is suitable for general referral hospitals with a moderate infrastructure. Expand
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Antibiotic prescription behaviours in Lao People's Democratic Republic: a knowledge, attitude and practice survey
Abstract Objective To assess the antibiotic prescribing practices of doctors working in the Lao People's Democratic Republic and their knowledge of local antibiotic resistance patterns. MethodsExpand
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Melioidosis, Phnom Penh, Cambodia
We describe 58 adult patients with melioidosis in Cambodia (2007–2010). Diabetes was the main risk factor (59%); 67% of infections occurred during the rainy season. Bloodstream infection was presentExpand
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Diversity of life-threatening complications due to Mediterranean spotted fever in returning travelers.
BACKGROUND Mediterranean spotted fever (MSF) is a tick-borne infection caused by Rickettsia conorii conorii mainly endemic in the Mediterranean Basin. Although usually considered as a benign disease,Expand
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