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Antibiotic resistance-the need for global solutions.
The causes of antibiotic resistance are complex and include human behaviour at many levels of society; the consequences affect everybody in the world. Similarities with climate change are evident.… Expand
mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients
Background:In an effort to raise protective antiviral immunity, dendritic cell immunotherapy was evaluated in six adults infected with human immunodeficiency virus (HIV)-1 and stable under highly… Expand
Transcriptome analysis of monocyte-HIV interactions
BackgroundDuring HIV infection and/or antiretroviral therapy (ART), monocytes and macrophages exhibit a wide range of dysfunctions which contribute significantly to HIV pathogenesis and… Expand
Antibiotic stewardship in low- and middle-income countries: the same but different?
- J. Cox, E. Vlieghe, +5 authors G. Levy Hara
- Clinical microbiology and infection : the…
- 1 November 2017
BACKGROUND Antibiotic resistance (ABR) is a quickly worsening problem worldwide, also in low- and middle-income countries (LMICs). Appropriate antibiotic use in humans and animals, i.e. antibiotic… Expand
A retrospective observational study on the efficacy of colistin by inhalation as compared to parenteral administration for the treatment of nosocomial pneumonia associated with multidrug-resistant…
- R. Naesens, E. Vlieghe, W. Verbrugghe, P. Jorens, M. Ieven
- BMC infectious diseases
- 15 November 2011
BackgroundColistin is used as last treatment option for pneumonia associated with multidrug-resistant (MDR) Pseudomonas spp.. Literature about the best administration mode (inhalation versus… Expand
Clinical Utility of the Nonstructural 1 Antigen Rapid Diagnostic Test in the Management of Dengue in Returning Travelers With Fever
Abstract Background Rapid diagnostic test (RDT) detecting the nonstructural 1 (NS1) antigen is increasingly used for dengue diagnosis in endemic and nonendemic settings, but its clinical utility has… Expand
Clinical bacteriology in low-resource settings: today's solutions.
- S. Ombelet, Jean-Baptiste Ronat, +7 authors J. Jacobs
- Computer Science, Medicine
- The Lancet. Infectious diseases
- 1 August 2018
We explore what constitutes successful implementation of clinical bacteriology in low-resource settings and describe a framework for implementation that is suitable for general referral hospitals with a moderate infrastructure. Expand
Antibiotic prescription behaviours in Lao People's Democratic Republic: a knowledge, attitude and practice survey
- F. Quet, E. Vlieghe, +8 authors J. Jacobs
- Bulletin of the World Health Organization
- 3 March 2015
Abstract Objective To assess the antibiotic prescribing practices of doctors working in the Lao People's Democratic Republic and their knowledge of local antibiotic resistance patterns. Methods… Expand
Melioidosis, Phnom Penh, Cambodia
We describe 58 adult patients with melioidosis in Cambodia (2007–2010). Diabetes was the main risk factor (59%); 67% of infections occurred during the rainy season. Bloodstream infection was present… Expand
Diversity of life-threatening complications due to Mediterranean spotted fever in returning travelers.
- R. Demeester, M. Claus, M. Hildebrand, E. Vlieghe, E. Bottieau
- Journal of travel medicine
- 1 March 2010
BACKGROUND Mediterranean spotted fever (MSF) is a tick-borne infection caused by Rickettsia conorii conorii mainly endemic in the Mediterranean Basin. Although usually considered as a benign disease,… Expand